Int. J. Curr. Res. Chem. Pharm. Sci. (2018). 5(8): 10-19 © 2018, IJCRCPS. All Rights Reserved 10 INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN CHEMISTRY AND PHARMACEUTICAL SCIENCES (p-ISSN: 2348-5213: e-ISSN: 2348-5221) www.ijcrcps.com DOI: 10.22192/ijcrcps Coden: IJCROO(USA) Volume 5, Issue 8 - 2018 Research Article Standardization of the drug Parangipattai chooranam – A Siddha herbal formulation. R. Vinodini 1* , M. Amala 1 , A. M. Amala Hazel 2 , M. Meenakshi Sundaram 3 , V. Banumathi 4 . 1 PG Scholar, Department of Kuzhandhai Maruthuvam, National Institute of Siddha, Chennai - 47. 2 Lecturer, Department of Kuzhandhai Maruthuvam, National Institute of Siddha, Chennai-47. 3 Associate Professor, Department of Kuzhandhai Maruthuvam, National Institute of Siddha, Chennai - 47. 4 Director, National Institute of Siddha, Chennai - 47. *Corresponding Author: vinodini02@gmail.com Abstract Siddha system of medicine is the system that distinctly explains the complete integrated relation of body, sense, mind and soul with the universe to attain immortality. “Siddha system of medicine is an evolution and not an overnight invention”. In Siddha medicine there are 32 types of Internal medicine and 32 types of external medicine. Chooranam is one among the 32 types of internal medicine. Parangipattai chooranam is a familiar polyherbal formulation in Siddha system of medicine which is selected by the author for standardisation. Aim of this study was to assess the quality of the drug Parangipattai chooranam by conducting physicochemical analysis, preliminary phytochemical analysis and other analytical techniques. Physicochemical analysis and preliminary phytochemical analysis was done based PLIM reference. Other analytical technique like High Performance thin layer chromatography (HPTLC) finger printing was done using CAMAG. The physicochemical analysis of the drug Parangipattai choornam showed that the pH value of 4.8 indicates the drug is slightly acidic. The preliminary phytochemical analysis showed the presence of Flavonoids, steroids, triterpenoids, coumarin, phenol, tannin, saponin and sugar. The drug was free of microbial contamination; heavy metals and pesticide were below deductible limit. The results obtained indicate that the drug is of standard quality and can be used as reference standard in laying pharmacopoeia standard. Keywords: Parangipattai chooranam, Physicochemical analysis, Standardization, Siddha medicine. Introduction Siddha system of medicine remains the one which I admired more. Siddhars, are the creators of this delightful system. Carvings of our Siddhars are still an astonishing one. Every country has its own system of medicine. Likewise in our country siddha system of medicine is most popular. Due to recent scientific research methods Siddha system of medicine is not fully accepted by other system of medicine and moreover not recognized by other countries. Accordingly Siddha research scholars are in need to prove the efficacy of each and every formulations carved by our great Siddhars. Standardisation method for all AYUSH drugs of Indian system of Medicine may contain a single herb or combination of different herbs believed to have complementary and or synergistic effects. Both the raw and finished products contain complex mixtures of fatty acids, sterols, alkaloids, flavonoids, glycosides etc. In the modern era due to commercialization and bulk production of herbal drugs there is chance of adulteration and imperfect processing of drugs. Hence there is need for standardization of all herbal drugs to sustain their quality. Therefore it is extremely desirable that these drugs should be characterized with modern DOI: http://dx.doi.org/10.22192/ijcrcps.2018.05.08.003