IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 18, Issue 9 Ser.4 (September. 2019), PP 68-75 www.iosrjournals.org DOI: 10.9790/0853-1809046875 www.iosrjournals.org 68 | Page “A comparative study of Alveogyl and ZOE in dry socket syndrome” Dr. Amit Yadav 1 , Dr. Anish Kumar 2 , Dr. Shivam Agrawal 3 , Dr. Renu Malik 4 , Dr. Tapan Kumar Mandal 5 ,Dr.Shadab Ahmed. 6 (Department of oral and maxillofacial surgery/ Teerthanker Mahaveer Dental College Moradabad ,U.P.) Corresponding Author: Dr. Amit Yadav Abstract: Alveolar Osteitis (dry socket) can be defined as the inflammation of the extraction socket occurring postoperatively within 1-4 days that is usually characterized by intense throbbing pain, accumulation of disintegrated clot and food debris in the socket and malodor. The etiology of the dry socket has not been well- known. However, certain theories suggest that the contributing factors to the etiology that includes early dislodgment of blood clot of extraction site, also any trauma due to surgery, secondary infection, or any nutritional deficiency, or mechanical dislodgement of any clot, also decreased the particularly vascularity, drug-induced includes oral contraceptives, and tobacco-induced. Alvogyl (Septodont, France) isan intra-socket medication for dry socket containing Iodoform (15.8%) as an antimicrobial, Butlyparaminobenzoate (25.7%) as an anaesthetic, Eugenol (13.7%) which retards the inflammatory process and also relief the pain by inhibiting the action of prostaglandins and Penghawar (3.5%) as an anti-inflammatory agent.This prospective study is aimed at evaluating the efficacy of Alvogyl in alleviating symptoms of dry socket when compared to the traditional method of ZOE paste.Null hypothesis states that there is no difference between Alvogyl & ZOE in treatment of dry socket. The alternate hypothesis states that Alvogyl is better than ZOE in treatment of dry socket. Conclusion:- The main objective of dry socket management has been palliative because pain level differs in every person. It is of greater importance to find and also access various parameter to provide us with more detailed compression in relation to its treatment modalities. In our study by comparing the above parameters between Alveogyl and ZOE,we conclude that Alvogyl has better healing properties and relieves pain at faster rate than ZOE. --------------------------------------------------------------------------------------------------------------------------------------- Date of Submission: 26-08-2019 Date of Acceptance: 10-09-2019 --------------------------------------------------------------------------------------------------------------------------------------- I. Introduction Alveolar Osteitis (dry socket) can be defined as the inflammation of the extraction socket occurring postoperatively within 1-4 days that is usually characterized by intense throbbing pain, accumulation of disintegrated clot and food debris in the socket and malodor 1 . Crawford in the year 1896 gave the term“Dry socket”. 2,3,4 Dry socket is a very common complication that is encountered in the healing phase for extraction. If wound arises within a few days after the extraction. Dry socket is characterized by extreme pain and foul odor, but with no suppuration. On clinical examination, the common clinical signs include the exposed bone with necrosis and sequestration of fragments. Healing of such wounds is extremely slow. The etiology of the dry socket has not been well-known. However, certain theories suggest that the contributing factors to the etiology that includes early dislodgment of blood clot of the extraction site, also any trauma due to surgery, secondary infection, or any nutritional deficiency, or mechanical dislodgement of any clot, also decreased the particularly vascularity, drug induced includes oral contraceptives and tobacco-induced. Other causes include decreased bleeding because of the hemostasis caused by epinephrine or other injectable substances that causes vasoconstriction in the local anesthetic and loss of clot because of rinsing the mouth or sucking the wound 5 . Frequency of alveolar osteitis or dry socket is increased with the cases of excessive traumatic type extraction, particularly in the procedures which involves flap reflection and also excessive amount of bone removal. The most common procedure is the mandibular third molar surgery which involves trimming of thick bone and also splitting of the tooth. Thus it is the commonest site for the occurrence. Several studies indicate that prevention is always the method of choice to decrease the rate of dry socket. These comprise of the use of 0.12% Chlorhexidine mouth wash, the placement of medicated packing into the extraction socket and the prophylactic use of Metronidazole and Lenampicillin, although none of the methods has gained a universal success for treating the dry socket. Usage of the Antibiotic coverage is an effective method to control the effect of the dry