IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 18, Issue 11 Ser.4 (November. 2019), PP 68-71 www.iosrjournals.org DOI: 10.9790/0853-1811046871 www.iosrjournals.org 68 | Page “Prevalence of Pyogenic Granuloma among Dental Patients in Northern India: An Original Research” Dr. SharibAbdus Salam 1 ,Dr.Hanjala Safi Rayeen 2 , Dr. Mobeen Khan 3 , Dr. Nazish Akhtar 4 , Dr. Nimrah Kawoos 5 . 1. Senior lecturer, Department of Periodontics and Implantology, Government Patna Dental College and Hospital, Patna. 2. Senior lecturer, Department of Oral Pathology and Microbiology, ChandraDentalCollegeandHospital,SafedabadBarabanki. 3. Senior lecturer, Department of OralMedicine and Radiology, ChandraDentalCollege and Hospital, SafedabadBarabanki. 4. Seniorlecturer,DepartmentofOralMedicineandRadiology,Seema Dental College and Hospital Rishikesh, Uttarakhand. 5. MDS, Pedodontics, Private Practitioner Florence Hospital Chanpora, Srinagar, Kashmir. Corresponding author: Dr. SharibAbdus Salam; Senior lecturer, Department of Periodontics and Implantology, Government Patna Dental College and Hospital, Patna. BACKGROUND:Pyogenic granuloma is a very common, non‑ neoplastic reactive growth of the oral cavity. Conservative surgical excision is the main line of treatment. Other treatment modalitie is cryosurgery, or lasersurgery. Scar formation and recurrence are the main post treatment complications. MATERIALS AND METHODS:500 patients were included in this study in which 325 patients weremale and 175 patients were female.Patients with 18 to 65 years of age were included in this study. Patients with severe reduced mouth opening were excluded from the study. Collected data was analyzed by using software SPSS 16. RESULTS:Out of 325 male patients, 36 (11.08%) patients were diagnosed with pyogenic granuloma and out of 175 female patients, 22 (12.57%) patients were diagnosed with pyogenic granuloma. CONCLUSION:Pyogenic granuloma is more common in female than male. KEYWORDS:Pyogenic Granuloma; Cryosurgery. --------------------------------------------------------------------------------------------------------------------------------------- Date of Submission: 28-10-2019 Date of Acceptance: 12-11-2019 --------------------------------------------------------------------------------------------------------------------------------------- I. Introduction Pyogenicgranulomaorgranulomapyogenicumisacommontumor‑ likegrowthoftheoralcavityorskinconsid eredtobe non‑ neoplasticin nature 1 .The accurate etiology and pathogenesis of pyogenic granuloma(PG) is still not obvious although, many researchers mentioned that pyogenic granuloma occurred due to an intensive reaction of localized connective tissue to a little irritating factor 2 . Many etiological factors for pyogenic granuloma have been reported for instance, primary teeth exfoliation, eruption of adult teeth ,traumatic factors, hormonal change , gingival inflammation ,chronic irritant factor, medications, vascular lesions, defective restoration, food accumulation or strange object and calculus in the gingiva and poor oral hygiene status 3 .Later, in 1904, Hartzell termed it as granuloma pyogenicum. It is the most common nonneoplastic tumor-like growth of the oral cavity. PG is a reactive tumor which arises in response to various stimuli due to local irritation and traumatic activity of tumor cells and on the rate of cell death. Prevalence of PG is more common in females in the second decade of life, probably due to vascularization effect of estrogen and progesterone 4 . Although PG does not show infiltrative tendency or malignant transformation potential, the recurrence rate after simple excision is comparatively high about 15.8% and requires a re-excision of the lesion in the near future 5 .Diagnosis of pyogenic granuloma (PG) depends on clinical, Histopathological and Radiographical examinations. “peripheral giant cell granuloma”, “hyperplastic gingival inflammation”, “Kaposi’s sarcoma” “peripheral odontogenic fibroma”, “peripheral ossifying fibroma”, “angiosarcoma” and “hemangioma” should be consider in differential diagnosis of pyogenic granuloma 6 . Pyogenic granuloma is a common benign vascular tumour occurring in all ages. Both skin and mucous membranes can be affected. The tumour consists of capillary proliferations, venules and fibromyxoidstroma. The development of a lesion occurs in three stages and bleeding is a common symptom. The tumour can mimic various other vascular lesions, solid tumours, and soft tissue infections. In recent years, targeted tumour therapies have become the most common cause of drug-induced