IOSR Journal of Applied Physics (IOSR-JAP) e-ISSN: 2278-4861.Volume 11, Issue 4 Ser. II (Jul. – Aug. 2019), PP 25-30 www.iosrjournals.org DOI: 10.9790/4861-1104022530 www.iosrjournals.org 25 | Page Assessment of Ventricular Volumes and Ejection Fraction using Echocardiography in Cardiac Diseases Sawsan A. A. Osman* 1 ,Nagla H. M. Khalid 2 , Mohamed E. M. Gar-Elnabi 1 1 Sudan University of Science and Technology. College of Medical Radiological Sciences P.O.Box 1908, Khartoum, Sudan 2 Najran University, Faculty of Applied Medical Sciences Corresponding Author: Sawsan Osman Abstract: Assessment of Ventricular Volumes and Ejection Fraction using Echocardiography in Cardiac Diseases were the demographic and measurement information presented as mean ± standard deviation, for the age and body mass index was 53.46 ± 16.24 year and 25.48 ± 6.09 kg/cm 2 , and the measurement data the end diastolic volume and end systolic volume was 98.51 ± 40.11 and 56.20 ± 23.22 while the ejection fraction 0.607 ± 0.149 percent. And correlate between the age group with the risk factor for hypertension patient was the biggest number of up normal patients in this study with 25 patients then the diabetes mellitus with 13 patients while the normal patients were 32 one. For the age group the patients in range 40-60 years represent a half of total number of patients. Using t-test to correlate between the ventricle volume and patients age were found that there is no significant difference between the end diastolic volume and systolic volume with patients age while there is a significant difference between the ejection fraction with patients age. correlate between the end systolic volume with patients age using regression equation found that the rate of change for the end systolic volume was decrease by rate 0.0799 for each year for patient’s fig 1. correlate between the end diastolic volume with patients age using regression equation found that the rate of change for the end diastolic volume was increase by rate 0.0211 for each year for patient’s. correlate between the ejection fraction with patients age using regression equation found that the rate of change for the ejection fraction was increase by rate 0.0002 for each year for patient’s. Keywords: Echocardiography, Ventricular Volumes, End Diastolic Volume, Ejection Fraction -------------------------------------------------------------------------------------------------------------------------------------- Date of Submission: 26-07-2019 Date of acceptance: 10-08-2019 --------------------------------------------------------------------------------------------------------------------------------------------------- I. Introduction Echocardiography has been characterized as the diagnostic method of choice for the morphological and functional study of cardiac structures because it has a good anatomical correspondence and good reproducibility in addition to being a low-cost, easy-to-perform procedure. Nonetheless, two-dimensional echocardiography, which is currently the most frequently used technique for the structural analysis of the heart, has limitations regarding the observation of the cardiac anatomy. This is due to the geometric assumptions for the calculation of cardiac diameters and volumes taken from a limited number of observation planes [1-7]. Greater anatomical divergence occurs in the presence of cardiac chamber dilatation. Three-dimensional echocardiography (RT-3D- Echo) was thus developed, enabling the structural visualization from multiple simultaneous observation planes, which provides greater proximity to real anatomy. The assessment of cardiac volumes and ejection fraction has valuable diagnostic, prognostic and therapeutic implications for patients suffering from left ventricular dysfunction [8–14]. With the increased recognition of the process of cardiac remodeling, and the advent of therapeutic interventions to mediate this, single or multiple estimates of volumes and ejection fraction are frequently used to assess an individual’s need for and response to treatment. Furthermore, many therapeutic trials use these parameters as a threshold for randomization or as a primary outcome measure. Currently, the three commonly used non-invasive methods are echocardiography (echo), radionuclide ventriculography and cardiovascular magnetic resonance. Echocardiography has been widely used as it is readily available and non-invasive. It does, however, dsuffer a number of limitations. M-mode echo is acoustic window and operator dependent and relies on geometric assumptions that do not hold true in patients with dilated, remodelled ventricles [15]. The assumption that a single segment is representative of the entire left ventricular is particularly problematic in patients with wall motion abnormalities [16]. 2D echo overcomes some of these problems but still extrapolates data from a limited sampling of the left ventricle and is highly dependent on good endocardial border definition.