52 Advances in Medical, Dental and Health Sciences Vol. 2 ● Issue 4 ● Oct-Dec 2019 ● www.amdhs.org RESEARCH ARTICLE AMDHS ADVANCES IN MEDICAL, DENTAL AND HEALTH SCIENCES OPEN ACCESS e-ISSN: 2581-8538 Received: 12 October 2019; Accepted: 16 December 2019 *Correspondence to: Dr. Aadil Ameer Ali PPDPT Scholar, Isra Institute of Rehabilitation Sciences, Karachi, Sindh-75300, PAKISTAN. Email: aadilamirali@hotmail.com Copyright: © the author(s), publisher and licensee OZZIE Publishers. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. This is an open access article distributed under the terms of the Creative Commons Attribution- NonCommercial-ShareAlike 4.0 License Aadil Ameer Ali 1, *, Noman Haq 2 , Kainat Chang 1 , Sana Naqi 3 , Muhammad Rafque 4 , Muhammad Ismail 4 , Rabbia Naseer 1 , Aqeel Nasim 5 , Muhammad Kumail 3 1 Department of Physical Therapy and Rehabilitation Sciences, Isra University, Karachi, PAKISTAN. 2 Faculty of Pharmacy and Health Sciences, University of Balochistan, Quetta, PAKISTAN. 3 Institute of Physiotherapy and Rehabilitation Sciences, Liaquat University of Medical and Health Sciences, Jamshoro, PAKISTAN. 4 Department of Statistics, University of Sindh, Jamshoro, PAKISTAN. 5 Pharmacist, Balochistan Institute of Nephro-Urology, Quetta, PAKISTAN. Abstract Many frail older adults are slim, weak and under nourished; this part of frailty remains a critical concern in the old age. However, there is also strong conformation that excessive obesity contributes to frailty, therefore, present study was conducted to assess the Relationship between Obesity and Frailty in Older Population of Karachi, Pakistan. A cross sectional survey was conducted in different hospitals of Karachi, Pakistan from January to March 2018. BMI was measured by standard procedure in already diagnosed 377 patients of Fraility (mild and sever) and SPSS version 23 was used to analyze the data. The majority were (n=215, 57%) male and having age between 61 to 63 years (n=75, 19.9%), overweight (n=151, 40%) and Obese were (n=37, 9.8%) no significant correlation was found between obesity and frailty. This Study concluded that there is no significance of obesity on Fraility, because mostly the government facilities are being attended by the poor patients and the rich patients who may have the obesity along with Fraility may go to the private institutes. Key words: Obesity, Fraility, Older Population, Karachi, Pakistan. Impact of Obesity on Frailty in Older Population of Karachi, Pakistan ACCESS THIS ARTICLE ONLINE WWW.AMDHS.ORG DOI : 10.5530/amdhs.2019.4.15 INTRODUCTION Many frail older adults are slim, weak and under nourished; this part of frailty remains a critical concern in the old age. However, there is also strong conformation that excessive obesity contributes to frailty by decreasing the ability of older adults to perform activities of daily living/life along with decreased metabolic stability. [1] As the Characterstics of frailty, proposed by Fried et al. which includes five components: decreased level of physical activity along with decreased muscle strength, self-reported fatigue, decreased walking speed, unintended weight loss and overtiredness. Moreover, the presence of one or two measures characterizes the pre-frailty condition, while more than three criteria characterize frailty. [2] Frailty is considered a forecast of adverse results, such as: its negative impact on health-related quality of life, the utilization of healthcare services and health conditions comorbidities, falls, institutionalization, disability, mortality along with its prevalence which is especially relevant with the domain of public health. [3,4] Early identification of subgroups of the population could be beneficial for planning for the capability of health and social systems to care for increasing numbers of frail older people over time. [5] Previous studies consistently demonstrated that frailty increased markedly with advancing age [6] Exploring factors that are associated with frailty is a basic research concern. Identification of correlates of frailty status facilitates the development of early preventive interventions of the occurrence of frailty. Studies exploring Published by : OZZIE PUBLISHERS