Available online www.jocpr.com Journal of Chemical and Pharmaceutical Research, 2015, 7(10):181-193 Research Article ISSN : 0975-7384 CODEN(USA) : JCPRC5 181 Effect of treatment durability and coloration of coated cotton fabrics on antibacterial, UV-blocking, healing and anti-inflammatory properties 1 Abeer A. A. Salama, 2 Rehab M. Kotb and 2 Rania N. Shaker 1 Pharmacological Department, National Research Centre, Cairo, Egypt 2 Textile and Clothing Department, Faculty of Women for Arts, Science, and Education, Ain Shams University, Cairo, Egypt _____________________________________________________________________________________________ ABSTRACT In the last few decades, there is a rising interest in personal health and hygiene textiles with protective properties are becoming an increasingly desirable aim of textile researchers, manufactures, and consumers. In this research modified cotton fabric surface using chitosan and/or alginate biopolymers, as well as titanium dioxide, zinc oxide, and their mixtures to impart vital and protective characteristics. The coated cotton fabrics were undergoing durability evaluation to repeated washing of antibacterial properties against Escherichia coli (E. coli) (Gram negative bacterium) and Staphylococcus aureus (S. aureus) (Gram positive bacterium) and the results revealed that excellent reduction% sustained up 30 washes. As well as very good and excellent UV protection category were maintained even after 30 washes. Healing and anti-inflammatory properties showed sustainability up to 10 washes but decreased after 30 washes. Furthermore, application of post-dyeing with reactive dye on the coated fabrics was done and the pre-treatment step to assess their dye-ability; showed a significant effect on the color strength (K/S) values. Hence, it could be proposed that the coated cotton fabrics maintained their protective properties as well as suitable for color coloration, which in turn make these finished and dyed cotton fabrics available for different textile and apparel applications. Keywords: Antibacterial, UV-blocking, anti-inflammatory, chitosan, alginate, metal oxides, dyeing, textile applications. _____________________________________________________________________________________________ INTRODUCTION In recent years, considerable attention has been paid to functional finishing for textile materials, such as antibacterial activity, ultraviolet (UV) protection, self-cleaning and wrinkle-free properties. Among these properties, the interest for antibacterial activity has been rapidly increasing, because all kinds of textile products, especially those made of natural fibers are sensitive to contamination and growth of pathogenic microorganisms [1]. The consumers are demanding textile products with higher performances, even in the traditional clothing and home textiles areas as the world market of textiles is becoming highly competitive [2]. Antibacterial finishing of textiles protects users from pathogenic or odor-generating microorganisms, which can cause medical and hygienic problems, and protects textiles from undesirable aesthetic changes or damage caused by rotting, which can result in reduced functionality [3]. Textiles have long been recognized as media to support the growth of microorganisms such as bacteria and fungi. These microorganisms are found almost everywhere in the environment and can multiply quickly when basic requirements, such as moisture, nutrients and temperature are met .Consumers’ demand for hygienic clothing and active wear has created a substantial market for antimicrobial textile products. Several antimicrobial agents have been used in the textile industry, chitosan, is the most non-toxic, biodegradable and biocompatible one [4]. Chitosan is a deacetylated derivate of chitin, which is a natural polysaccharide mainly derived from the shells of shrimps and other sea crustaceans. Chemically, it can be