J Women’s Health Dev 2020; 3 (2): 065-076 DOI: 10.26502/fjwhd.2644-28840018 Journal of Women’s Health and Development Volume 3 No 2 – June 2020 65 Research Article Comparison of the Clinical Process Outcomes of Non-Surgical and Surgical Treatment for Cornual Pregnancy : A Retrospective Randomized Case-Control Study Eun Hui Joo # , Ji Hyon Jang # , Bobae Lim, Eun Hee Ahn, Sang Hee Jung, Young Ran Kim * Department of Obstetrics and Gynecology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Korea * Corresponding Author: Young Ran Kim, Department of Obstetrics and Gynecology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Korea, Tel: 031-780-5290; Fax: 031-780-5069; E-mail: happyimam@naver.com/ happyiran@chamc.co.kr # - both the authors contributed equally. Received: 20 March 2020; Accepted: 30 March 2020; Published: 03 April 2020 Citation: Eun Hui Joo, Ji Hyon Jang, Bobae Lim, Eun Hee Ahn, Sang Hee Jung, Young Ran Kim. Comparison of the Clinical Process Outcomes of Non-Surgical and Surgical Treatment for Cornual Pregnancy : A Retrospective Random- ized Case-Control Study. Journal of Women’s Heal th and Development 3 (2020): 065-076. Abstract Objectives: To compare the clinical process outcomes of ultrasound (US) - guided intragestational sac injection of methotrexate (MTX) and cornual resection for cornual pregnancies. Methods: The retrospective case-control study included 31 women diagnosed with cornual pregnancy at a single center, between January 2007 and February 2017. Of these, we enrolled 31 women who had implantation in the cornual area at the time of diagnosis; 12 were treated with local injection of MTX under ultrasound guidance and 19 underwent with cornual resection. Procedure-related outcomes, including operating time, time to normal state β-hCG serum level, and hemoglobin level changes. Statistical significance was assessed using the chi-square test, Mann-Whitney test, and Student’s t-test.