Int J Pharm Bio Sci 2013 Oct; 4(4): (P) 722 - 728 This article can be downloaded from www.ijpbs.net P - 722 Research Article Pharmacology International Journal of Pharma and Bio Sciences ISSN 0975-6299 WOUND HEALING AND ANTIBACTERIAL ACTIVITIES OF THE CHLOROFORM EXTRACT OF GLINUS LOTOIDES LINN. IN ALBINO RATS K.SUDHA RAMESHWARI* 1 , M.KALEESWARI 1 AND A.THANGATHIRUPATHI 2 1 Department of Biochemistry, V.V.Vanniaperumal College for Women, Virudhunagar, Tamilnadu, India. 2 Department of Pharmacology, Sankaralingam Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi, Tamilnadu, India ABSTRACT Wound healing is a process which is fundamentally a connecting tissue response. Wound healing comprise of different phase such as contraction, epithelization, granulation and collagenation. Microbes easily enters into the wounds and causes infection.The present study has proved that the wound healing potential and antibacterial activity of chloroform extract obtained from Glinus lotoides Linn. showed significant effect. The animals administrated with the chloroform extract Glinus lotoides Linn. (CEGL) showed a high tensile strength and antibacterial activity. Flavanoides, glycosides may be attributed to the wound healing activity. KEY WORDS: Wound healing, Glinus lotoides Linn., Excision wound, Incision wound model. K.SUDHA RAMESHWARI Department of Biochemistry, V.V.Vanniaperumal College for Women, Virudhunagar, Tamilnadu, India.