Leukemia Detection using Object Oriented Method Dr. M. Rama Bai Sai Sreeja Alapati Computer Science Engineering Computer Science Engineering Mahatma Gandhi Institute of Technology Mahatma Gandhi Institute of Technology Hyderabad, India Hyderabad, India Abstract—Blood cancers affect the production and function of your blood cells. In most blood cancers, the normal blood cell development process is interrupted by uncontrolled growth of an abnormal type of blood cell. This paper will present an approach for the detection and tracking of Leukemia. This paper aims at identifying leukemia, by using image segmentation. A microscopic image of blood sample is taken, the cell count is extracted using image processing module by module. The purpose is to increase the accuracy using three different approaches object wise. I. INTRODUCTION This paper aims at identifying leukemia, by using image segmentation. An image is a way of transferring information, and the image contains lots of useful information. Understanding the image and extracting information from the image to accomplish works is an important area of application in digital image technology, and the first step in understanding the image is the image segmentation. Digital images were acquired using a digital camera connected to a light microscope. In practice, it is often not interested in all parts of the image, but only for some certain areas which have the same characteristics. Image segmentation is one of the hot spots in image processing and computer vision. It is also an important basis for image recognition. It is based on certain criteria to divide an input image into a number of the same nature of the category in order to extract the area which people are interested in. And it is the basis for image analysis and understanding of image feature extraction and recognition. In this paper we use region-based segmentation algorithm. Region-based segmentation algorithms operate iterative by grouping together pixels which are neighbors and have similar values and splitting groups of pixels which are dissimilar in value. The advantage of regional based growth is that it usually separates the connected regions with the same characteristics and provides good boundary information and segmentation results. The idea of regional based growth is simple and requires only a few seed points to complete. And the growth criteria in the growing process can be freely specified. Finally, it can pick multiple criteria at the same time. Blood Cancer is a disorder that affects around 1.2 million people worldwide every year. Blood cancer, or hematologic cancers, affect the production and function of blood cells. Most of these cancers start in the bone marrow where blood is produced. Their symptoms usually come on slowly, so you might not even notice them. And some people have no symptoms at all. Fig. 1. Normal vs. Effected Cells Referring to the images in Fig 1, the left image shows us the composition of blood cells of a normal human being with a high number of red blood cells whereas the right one is of a cancer affected human with high composition of white blood cells. The three most common types of Leukemia are Chronic lymphocyte, Hairy cell, Juvenile Myelomonocyte, Plasma cell, T- cell prolymphocyte. Chronic Lymphocyte (CLL), is the most common leukemia in adults. It’s a type of cancer that starts in cells that become certain white blood cells (called lymphocytes) in the bone marrow. The cancer (leukemia) cells start in the bone marrow but then go into the blood. In CLL, the leukemia cells often build up slowly. Many people don’t have any symptoms for at least a few years. But over time, the cells grow and spread to other parts of the body, including the lymph nodes, liver, and spleen. Hairy Cell Leukemia is a rare, slow-growing cancer of the blood in which your bone marrow makes too many B cells (lymphocytes), a type of white blood cell that fights infection. These excess B cells are abnormal and look "hairy" under a microscope. As the number of leukemia cells increases, fewer healthy white blood cells, red blood cells and platelets are produced. Hairy cell leukemia affects more men than women, and it occurs most commonly in middle-aged or older adults. Juvenile Myelomonocyte (JMML) is a rare childhood cancer that usually happens in children younger than 2 years old. In JMML, too many myelocytes and monocytes (two types of WBCs) are produced from immature blood stem cells called blasts. These International Journal of Engineering Research & Technology (IJERT) ISSN: 2278-0181 http://www.ijert.org IJERTV9IS050374 (This work is licensed under a Creative Commons Attribution 4.0 International License.) Published by : www.ijert.org Vol. 9 Issue 05, May-2020 471