International Journal of Pharma Research & Review, March 2014; 3(3):16-19 ISSN: 2278-6074 V Subramani et.al, IJPRR 2014; 3(3) 16 Research Article Plant Extracts Derived Silver Nanoparticles *V. Subramani, J. Jerome Jeyakumar, M. Kamaraj, B. Ramachandran PG and Research Department of Botany, Jamal Mohammed College, Tiruchirappalli, Tamil Nadu - 620 020, India. ABSTRACT Nanotechnology is a most promising field for generating new applications in medicine. The present investigation is highly warranted to through more light upon the Ag nanoparticles from medicinal plants will helpful to investigate the active principle action for biochemical and molecular fields. In this study, nanoparticles of 80 ± 90 nm were synthesized by using medicinal plants such as Mukia maderaspatana, Kedrostis foetidissima and Cayratia pedata, and are confirmed by SEM. These nanoparticles showed a characteristic absorption peak at 420 nm in UV spectra. The possibility of protein as a stabilizing material in silver nanoparticles is revealed by FTIR analysis. Keywords: Green synthesis, silver nanoparticles, mukia maderaspatana, kedrostis foetidissima, Cayratia pedata Received 22 Feb 2014 Received in revised form 07 March 2014 Accepted 09 March 2014 *Address for correspondence: V. Subramani PG and Research Department of Botany, Jamal Mohammed College, Tiruchirappalli, Tamil Nadu - 620 020, India. E-mail: v.subramani77@gmail.com INTRODUCTION Nanotechnology can be delineated as a researcher for the design, synthesis, and manipulation of structure of particles with dimension smaller than 100nm. A young offshoot of nanotechnology is Nanobiotechnology. It combines biological principles with physical and chemical processes to generate nano-sized particles with specific functions [1-3]. Nanotechnology represents an economic alternative for chemical and physical methods of nanoparticles formation. These methods of deduction can be divided on intracellular and extracellular [4]. Recently, metal nanoparticles have gained a great deal of attention due to their unique chemical, optical, magnetic, mechanical and electric magnetic properties. Thus, metallic nanoparticles are used in different applications such as electronics, catalysis and photons [5]. Nanotechnology is dynamically developing as an important area of innovative research with potential effects in electronics and medicine [6]. MATERIALS AND METHODS Study area and sampling The Mukia maderaspatana, Kedrostis foetidissima and Cayratia pedata plant materials were collected from Kolli hills, Namakkal district of Tamil Nadu in India during monsoon 2013. The fine powder of the plant material was sterilized at 121°C for 15 min and weighed. Sterilized fine powder, 20 g each was taken each plant, mixed with 200 ml of Milli Q water and held in boiling water bath at 60°C for 10 minute. The extracts were filtered with Whatman 1 filter paper and the filtered extracts were stored in a refrigerator at 4°C and it’s used as test samples. Biosynthesis of nanoparticles For the biosynthesis of silver nanoparticles, silver nitrate prepared at the concentration of 10 -3 M with pre-sterilized Milli Q water. A quantity of 1.5 cc of each extract was mixed with 30 ml of 10-3 M of silver nitrate for the synthesis of silver nano particles. Silver nitrate has taken in similar quantities of 1.5 ml each without adding plant extracts to main respective controls. The saline bottles were tightly covered with aluminum foil in