Indian Journal of Obstetrics and Gynecology Research 2019;6(4):495–498 Content available at: iponlinejournal.com Indian Journal of Obstetrics and Gynecology Research Journal homepage: www.innovativepublication.com Original Research Article Clinico-pathological correlation of AUB patients undergoing hysterectomy in a rural tertiary care centre Kondareddy Radhika 1, *, E Gomathy 1 1 Dept. of Obstetrics and Gynaecology, Sri Devaraj URS Medical College, Kolar, Karnataka, India ARTICLE INFO Article history: Received 17-02-2019 Accepted 14-09-2019 Available online 06-12-2019 Keywords: Heavy menstrual bleeding Abnormal uterine bleeding Hysterectomy Histopathology study Fibroid Adenomyosis Dysmenorrhea ABSTRACT Introduction: Abnormal uterine bleeding (AUB) usually occurs in peri or postmenopausal age group. Causes of AUB according acronym (PALM-COEIN) by FIGO (2011). They are–polyp, adenomyosis, leiomyoma, malignancy and hyperplasia, coagulopathy, Ovulatory dysfunction, endometrial, iatrogenic and not yet classified. Diagnosis was made by clinical examination, ultrasonography and confirmed by histopathology. Management can be medical, minor procedures D and C, ablative procedure and hysterectomy. Objectives: To find out the incidence and distribution of various uterine pathology in hysterectomy specimens with related to different age groups, parity and clinical features. Materials and Methods: A prospective study was conducted in the department of Obstetrics and Gynecology at R.L. Jalappa hospital attached to Sri Devaraj Urs Medical college, Kolar over a period of one year i.e June 2017 to May 2018. AUB cases (90) were examined. History taken about age, parity, clinical symptoms, duration and amount of blood loss. Information about gynaecological complaints, medical diseases, hormonal, operative treatment, general examination, systemic examination done and diagnosis made. Blood investigations, Pap smear and pelvic sonography done. Endometrial sampling sent for Histopathology. Hysterectomy specimens sent for Histopathology examination. Final diagnosis compared with clinical, ultrasonography and HPR. Results: Most of the patients belonging to the age group of 41-50 years and were multiparous. Common symptoms were heavy menustral bleeding HMB 48.89%. Indications was fibroid uterus 46.67%. Endometrial biopsy was proliferative endometrium 44.44%. Histopathological study specimen showed leiomyoma (40%). Fibroid diagnostic accuracy by clinical and Sonography methods are 85.7% and 92.3%. Endometrial patterns was proliferative simple endometrial hyperplasia in perimenopausal group and complex hyperplasia in postmenopausal group. Conclusion: Maximum patients were multiparous belonging to perimenopausal age. Common AUB symptom was HMB and diagnosis was leiomyoma which was confirmed by USG and histopathology. Hysterectomy remains definite treatment in AUB patients. © 2019 Published by Innovative Publication. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by/4.0/) 1. Introduction Uterus, the epitome of womanhood is influenced by cyclical hormonal changes under the influence of changes in hypothalamus-pituitary- ovary axis. Menstruation is the cyclic uterine bleeding experienced by all women of reproductive age group. Menstrual disorders are a common * Corresponding author. E-mail address: radhi.konda91@gmail.com (K. Radhika). indication for medical visits among women of reproductive age and heavy menstrual bleeding affects up to 30% of women throughout their reproductive lifetime. 1,2 Abnormal uterine bleeding (AUB) is one of the most frequently encountered and perplexing condition in adult women. 3 AUB may be defined as any variation from the normal menstrual cycle, & includes changes in regularity & frequency of menses, in duration of flow, or in amount of blood loss. 4 https://doi.org/10.18231/j.ijogr.2019.107 2394-2746/© 2019 Innovative Publication, All rights reserved. 495