Original Research Article *Corresponding Author: Sunil Kishore, Dept. of Paediatrics, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India Email: dr.sunil2k2@gmail.com http://doi.org/10.18231/j.ijmpo.2019.020 IP International Journal of Medical Paediatrics and Oncology, July-September, 2019;5(3):89-92 89 Available online at www.iponlinejournal.com Journal homepage: www.innovativepublication.com/journal/ijmpo Clinical profile and outcome in a paediatric intensive care unit in tertiary level centre of Bihar Ravindra Kumar 1 , Sunil Kishore 2* , Rakesh Kumar 3 , Jayant Prakash 4 1 Senior Resident, 2 Assistant Professor, 3 Additional Professor, 4 Professor, Dept. of Paediatrics, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India Abstract Aim: To study was to analyze demographic profile and outcome in a tertiary care hospital Pediatric Intensive care (PICU) in Indira Gandhi Institute of Medical Sciences, Bihar. Materials and Methods: This Retrospective study was carried out in Indira Gandhi Institute of Medical Sciences, Bihar from August 2018 to July 2019. Results: A total of 384 patients were admitted during the period. Out of total admissions 246(64%) were male and 138(36%) were girls. Mechanical ventilation rate was 67(17.4%). 57 patients died in PICU given a mortality rate of 13.8%. The mean age was 5.2 years (ranging from 1 day to 14 years). Average length of Hospital stay was 8.26±6.6 days. Diagnoses included neurological (18.02%), respiratory (17.1%), renal (14.6%), infectious (9.8%), haematological (6.7%), cardiac (6.3%) other surgical (14.6%). Patients who died had statistically worse severity scores. Significant mortality risk factors were high inotropic score and PRISM III>10. Conclusions: Demographic profile of our PICU patients showed similar characteristics as those of reported in different relevant studies with minor differences in few aspects. The overall results of this study are encouraging and development of new PICUs in our state is the need of the day. Keywords: Pediatric intensive care unit, Pediatric risk of mortality PRISM III, Mortality. Introduction A pediatric intensive care unit (also paediatric), usually abbreviated to PICU, is an area within a hospital specializing in the care of critically ill infants, children, and teenagers. 1 There are studies documenting outcomes of Pediatric intensive care units (PICU) from other state of India 2 but no such studies are available from the Bihar. Parikh et al outlined significant issues in quality, cost and outcomes from an adult Intensive care unit (ICU) in India 3 Pollack et al showed a better outcome of PICU patients in units where there was a pediatric intensivist and/or a pediatric intensive care fellowship programme. 4 Numerous conditions that were previously fatal are now treatable. Moreover, there are references that support better outcome of PICU patients in tertiary centers, which led to the development of a centralized system of PICUs worldwide. 5-7 Aim of this retrospective studys was to study the clinical profile of children admitted to the pediatric intensive care unit of Indira Gandhi instituite of medical science and hospital, to find the disease distribution and the age distribution and the mortality rates. Material and Methods This retrospective study was carried out in Indira Gandhi instituite of medical science and hospital,Bihar which is tertiary care centre of Bihar and Pediatric intensive care was started on august 2018. So we retrospectively analysed our PICU record from August 2018 to July 2019. A total of 384 patients were admitted during the period. Data collected on patients included: age, gender, admission and discharge