Volume 01 | Issue 01 | January-2019 | Page 1 of 6 Xournals Academic Journal of Modern Applied Sciences Academic Journal of Modern Applied Sciences ISSN UA | Volume 01 | Issue 01 | January-2019 Role of Genetic and Environment in the Development of Disorder: Schizophrenia Kavit S. Mehta 1 Available online at: www.xournals.com Received 3 rd September 2018 | Revised 6 th October 2018 | Accepted 8 th December 2018 Abstract: Human population have one of most common, devastating and least understood neuropsychiatric illness that is schizophrenia. This disorder is generated by the action of genetic and environmental effects. Genome-wide association studies (GWAS) shows the result that more than 100 loci has been identified which have high risk of schizophrenia. Monozygotic twins have a high risk of this disorder as compare to the dizygotic disorder. Different models has been developed to find the relation between genetic and schizophrenia. In the same way, Environmental is also a factor that give their impact in the generation of schizophrenia. In environmental factors, parental, perinatal, season birth and so on may be the cause of schizophrenia. But it is found that individually genes or individually environment is not responsible for the development of disorder. The gene as well as environment both are necessary to produce the disorder. This paper represents the role of genetic and environment in the development of schizophrenia disorder. Keywords: Schizophrenia, Genetics, Perinatal, Monozygotic Authors: 1. Mehsana Urban Institute of Sciences, Ganpat University, Ganpat vidyanagar, Gujarat, INDIA Xournals