International Journal of Research & Review (www.ijrrjournal.com) 424 Vol.6; Issue: 8; August 2019 International Journal of Research and Review www.ijrrjournal.com E-ISSN: 2349-9788; P-ISSN: 2454-2237 Original Research Article Prevalence of Thyroid Disorders in Pregnancy Sudha Sharma 1 , Dinesh Chandra Sharma 2 1 Associate Professor, Department of Obstetrics & Gynaecology, Ananta Institute of Medical Sciences, Rajsamand, Rajasthan, India 2 Associate Professor, Department of General Medicine, Ananta Institute of Medical Sciences, Rajsamand Corresponding Author: Dinesh Chandra Sharma ABSTRACT Objective: The present study was carried out to find out the prevalence of various thyroid disorders among pregnant women in their first trimester in the southern area of Rajasthan. Material & Methods: The study was conducted during the period of 1year from July 2017 to July 2018. 200 pregnant women attending antenatal clinic for their routine antenatal visit in first trimester were included in the study. Routine blood and urine investigations along with serum TSH, FT3 and FT4 were done in all the study participants. Results: Age of the patient’s ranged from 19 to 38 with the mean age of 25.66±3.90 years. Mean gestational age of study population was 8.12±1.63 weeks. The mean TSH, FT3 and FT4 values were 1.499, 2.386 and 1.410 respectively. Thyroid disorders were found in 14%patients out of 200 study participants. 86% patients were euthyroid among the study participants. 7% patients were found to be having subclinical hypothyroidism. 4% were having overt hypothyroidism and 3% were having subclinical hyperthyroidism. Conclusion: The study revealed high prevalence of thyroid disorders (14%) among pregnant women in their first trimester specially hypothyroidism (11%). Routine antenatal thyroid screening should be performed in all pregnant women. Keywords: Hypothyroidism, antenatal, hyperthyroidism, eclampsia INTRODUCTION Normal thyroid hormone levels are necessary in maintaining pregnancy and in development of fetus. Thyroid dysfunctions are more common in female than in male. Maternal thyroid functions changes during pregnancy and leads to thyroid disorders in absence of adaptation to these changes. Thyroid disorders during pregnancy can result in substantial adverse fetomaternal outcomes. Furthermore, thyroid dysfunction can be readily diagnosed with simple and reliable blood tests and easily corrected with economical and easily available treatments. (1) Worldwide, thyroid disorders are common in women of child-bearing age. (2) During pregnancy, demands on the hypothalamic-pituitary-thyroid axis increases which commonly leads to borderline thyroid abnormalities. Both hyper and hypo-thyroidism types of thyroid disorders can occur during pregnancy and correction of these disorders dramatically reduces the risk of adverse fetomaternal outcomes like foetal loss, preterm birth, pre- eclampsia and eclampsia and maternal morbidity. (3, 4) According to the western literature, the prevalence of hypothyroidism in pregnancy is around 2.5%. The prevalence of gestational diabetes is around 0.1–0.4% and that of thyroid autoimmunity (TAI) is around 5-10%. (5)