1 1 Final Revised ver#5 from June 10, 2020 in response to peer reviewers Corrected further ver#6 from June 19 2020. Contact author Supp information At pre-print server https://vixra.org/abs/2006.0011?ref=11360015 Analysis of APOBEC and ADAR deaminase-driven Riboswitch Haplotypes in COVID-19 RNA strain variants and the implications for vaccine design Edward J. Steele 1,2 and Robyn A. Lindley 2,3,4 1 CYO'Connor ERADE Village Foundation, 24 Genomics Rise, Piara Waters, 6112 2 Melville Analytics Pty Ltd, Melbourne, Vic, AUSTRALIA 3 GMDxCo Pty Ltd, Melbourne, Victoria, AUSTRALIA; 4 Department of Clinical Pathology, The Victorian Comprehensive Cancer Centre, Faculty of Medicine, Dentis- try & Health Sciences, University of Melbourne, Victoria, AUSTRALIA. Running head: Analysis of Deaminase Signatures in COVID-19 Correspondence: A/Professor Edward J Steele, Melville Analytics Pty Ltd, 162 Collins Street, Melbourne 3000, email: e.j.steele@bigpond.com Key words: COVID-19 genomes; Coronavirus pandemic; Single Nucleotide Variations; Cytosine and Adeno- sine Deaminations; AID/APOBEC and ADAR Deamination Motifs Author Information: Edward J. Steele e.j.steele@bigpond.com Robyn A. Lindley robyn.lindley@gmdxgroup.com