International Journal of Research & Review (www.ijrrjournal.com) 196 Vol.5; Issue: 11; November 2018 International Journal of Research and Review www.ijrrjournal.com E-ISSN: 2349-9788; P-ISSN: 2454-2237 Original Research Article Incidence of Fungal Rhinosinusitis in Bihar and Its Management Shelendra Kumar Gupta a , Ranjeet Singh b , Anjali Gupta c a Assistant Professor, Department of ENT, KM Medical College and Hospital, Sonkh Road, Mathura, Uttar Pradesh, India. b Assistant Professor, Department of Medicine, KM Medical College and Hospital, Sonkh Road, Mathura, Uttar Pradesh, India. c Lecturer, Department of Anatomy, SN Medical College, Agra, Uttar Pradesh, India. Corresponding Author: Ranjeet Singh ABSTRACT Introduction: Chronic rhinosinusitis is a clinical syndrome manifested by a prolonged inflammatory response of the nasal and sinus mucosa and the underlying bone. This entity is often associated with the presence of allergic and non-allergic rhinitis as well as nasal polyposis Aims and objectives: To evaluate the incidence of fungal rhinosinusitis in Bihar and its management. Materials and methods: 50 patients of Chronic rhino-sinusitis undergoing Functional endoscopic sinus surgery, Caldwell Luc operation, Antral Puncture wash and treated post-operatively with oral corticosteroid and topical anti fungal drugs were studied to find out incidence of fungal rhino-sinusitis among the Chronic sinusitis patients. Results: The maximum number of cases was in age group of 11-30 years of age. Male to female ratio was 24:26 in CRS and 5:7 in FRS. Hindu patient were more common than Muslims. Most of the patient belongs to low socio-economic group. The role of personal history of allergic rhinitis in the precipitation of disease was appeared in 48% cases of CRS and 83.3% cases of FRS. Nasal obstruction, nasal discharge, headache, post nasal discharge and nasal polyposis are the commonest clinical presentation. The duration of symptoms ranged from 6 month to 3 years. Radiological finding especially CT scan and histopathological examination are major basis for the diagnosis. Conclusion: Although the result of oral & intranasal steroid and topical antifungal agents in our study is good, more study needs to be performed. Key words: Fungal rhinosinusitis, nasal and sinus mucosa, allergic and non-allergic rhinitis, nasal polyposis. INTRODUCTION Chronic rhinosinusitis is a clinical syndrome manifested by a prolonged inflammatory response of the nasal and sinus mucosa and the underlying bone. This entity is often associated with the presence of allergic and non-allergic rhinitis as well as nasal polyposis. Fungal sinusitis may occur in patients with chronic sinusitis, who usually have a predisposing cause such as neutropenia, AIDS, prolonged use of corticosteroids / broad spectrum antibiotics, uncontrolled diabetes, malnutrition or are immunosuppressed. A variety of different causative organisms could be responsible for fungal sinusitis. Aspergillus and mucor mycosis are the commonest. Non-invasive fungal sinusitis is usually due to aspergillosis. It mimics sinusitis but there is no response to antibiotics. Local clearance of fungus is required with medical