International Journal of Otorhinolaryngology and Head and Neck Surgery | July 2020 | Vol 6 | Issue 7 Page 1331 International Journal of Otorhinolaryngology and Head and Neck Surgery Kumar G et al. Int J Otorhinolaryngol Head Neck Surg. 2020 Jul;6(7):1331-1335 http://www.ijorl.com pISSN 2454-5929 | eISSN 2454-5937 Original Research Article Various spectrum of lesion in palatine tonsil underwent for tonsillectomy in tertiary care center: a two years retrospective study Gaurav Kumar 1 *, Ritu Sharma 2 , Desh Pal 1 , Geeta 1 INTRODUCTION Tonsillar and adenoid diseases are the most common health-related issues in ear, nose and throat (ENT) diseases in children and adults. 1 The palatine tonsils are paired nodular masses of lymphoid tissue situated on either side of the oropharynx having an extremely remarkable role in the antimicrobial defense of the body. 2 They are covered by non-keratinized stratified squamous epithelium along with deep crypts that invaginate into the parenchyma, in which B-lymphocytes are found. 3 Tonsillitis is one of the commonest infectious diseases seen commonly in the young age group. Various organisms including viruses like Reo virus, Adenovirus, Influenza virus and Echo virus, and bacteria like beta-hemolytic Streptococcus are implicated in causation of tonsillitis. Rarely, it can be caused by fungi or parasites. 4 Chronic tonsillitis is still the commonest indication for tonsillectomy. 5 One of the definite indications is asymmetric tonsil for histopathological evaluation to rule out malignancy. 6,7 ABSTRACT Background: Palatine tonsils are paired masses of lymphoid tissue which act as immunologic barrier against the entry of pathogenic organism into the respiratory and digestive tracts. Despite their protective function, tonsils are prone to infection. Chronic tonsillitis is a disease with repeated attacks of acute tonsillitis or a sub-clinic form of a resistant or poorly treated infection. Objective of the study was to know the various clinico-pathological finding in palatine tonsil underwent for tonsillectomy. Methods: This was a retrospective study where 105 cases (unilateral-15, bilateral-86 and tonsillar biopsy in 04) of histopathologically identified tonsillectomy specimens were included. The available data for all the patients as regards to age, sex and clinical symptoms was collected. Representative bits were taken from formalin fixed tonsillectomy specimens in which hematoxylin and eosin (H and E) staining was done. Results: Amongst the cases, 79 cases showed chronic tonsillitis. Other lesions were chronic tonsillitis with actinomycosis in 11 cases, acute on chronic tonsillitis in 07 cases, granulomatous tonsillitis in 03 cases, Acute ulcerative tonsillitis with micro abscesses in 01 case and Reactive lymphoid hyperplasia in 02 case. Two malignancies were observed - one case of poorly differentiated carcinoma and another case of lymphoma. Conclusions: This study showed that chronic tonsillitis is a common problem facing in all age groups and histopathology play a key role in diagnosing both benign and malignant lesion of tonsil therefore deciding the proper management. Keywords: Palatine tonsil, Tonsillectomy, Tonsillitis, Histopathology 1 Department of ENT, 2 Department of Pathology, T.S. Misra Medical College and Hospital, Lucknow, Uttar Pradesh, India Received: 16 April 2020 Revised: 17 May 2020 Accepted: 18 May 2020 *Correspondence: Dr. Gaurav Kumar, E-mail: kumargaurav.1014@gmail.com Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20202788