_____________________________________________________________________________________________________ *Corresponding author: Email: pkumar_gpu@yahoo.co.in; Review Article Asian Journal of Advances in Medical Science 2(1): 15-20, 2020 OVERVIEW ON CORONAVIRUS (COVID-19) PRADEEP KUMAR 1* 1 Department of Zoology, S. G. N. Government P. G. College, Muhammadabad, Gohna, Mau-276403 (U.P.), India. AUTHOR’S CONTRIBUTION The sole author designed, analysed, interpreted and prepared the manuscript. Received: 12 June 2020 Accepted: 27 June 2020 Published: 03 July 2020 ABSTRACT Coronavirus (COVID-19) is an important public health emergency of international concern. Firstly COVID-19 was isolated from Wuhan market in China at 7 Jan. 2020. As of this time, there is no known effective pharmaceutical treatment; although it is much needed for patient contracting severs form of the disease. This virus causes respiratory infection in human including sneezing, coughing, cold and pneumonia while in animal it causes diarrhea and upper respiratory diseases. COVID-19 is transmitted human to human or human to animal via airborne droplets. This disease can be diagnosis on the basis of travel history from infected areas, common symptom or by laboratory confirmations. WHO advised to avoid public place, close contact to Coronavirus infected persons, wearing mask, sanitizing hands and maintain social distancing for prevention. It’s also advised infected pensions keep in quarantine center for 14 days or separate from other family member to single separate room, implementation of contact, droplet precaution, and airborne precaution, keep physical distances. Some countries are also using lopinavir/ritonavir, remdesivir, chloroquine and hydroxychloroquine drugs for treatment of Coronavirus but these are not efficient in cure of this disease. The aim of the systematic review of literature is to summarize the evidence regarding COVID-19, symptoms, pathogenesis and prevention/treatment. Keywords: COVID-19; symptoms; epidemiology and viral management. 1. INTRODUCTION Coronavirus (COVID-19) are positive-sense, single stranded RNA viruses and its diameters is 60 nm to140 nm with spike like projection on it’s around which giving it a crown like appearance [1]. Their viral is RNA genomic and their ranges from 26 to 32 kilobases in length [2]. COVID-19 belongs to the Nidovirales order which includes Roniviridae, Arteriviridae, and Coronaviridae families [3]. The Coronviridae family is subdivided into Torovirinae and Coronavirinae subfamilies [3]. Coronavirinae is further sub classified into alpha, beta, gamma, and delta [3]. Phylogenetic clustering accounts from the classification of these subtypes of viruses. It can be isolated from different animal species. In 1960 first case of coronavirus was notified [4] and Canadian study in 2001 was identified approximately 500 patients as Flu-like system in which 17 to 18 cases were confirmed as infected with Coronavirus by polymerase chain reaction. These include livestock, birds, and mammals such as bats, camels, masked palm civets, dogs, mice, and cats [2]. In 2003, various reports were published the spreading of Coronavirus in many countries such as Hong Kong, United States America, Singapore, Vietnam, Thailand, Taiwan and their several case of severe acute respiratory syndrome which caused by Coronavirus and their mortally was more than 1000 patient [4]. Another study report in Hong Kong was confirmed 50 patients