International Journal of Health Sciences & Research (www.ijhsr.org) 261 Vol.8; Issue: 11; November 2018 International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249-9571 Original Research Article GC-MS Determination of Bioactive Compounds of Dendrophthoe falcata (L.F) Ettingsh: An Epiphytic Plant G. GnanaPriyanka Beulah 1 , P. Tresina Soris 2 , V.R Mohan 2 1 Research Scholar (18112232262009), PG & Research of Botany, VOC College Tuticorin 2 PG & Research of Botany, VOC College, Tuticorin – 628008 Corresponding Author: V.R Mohan ABSTRACT In this study, the bioactive compounds of D.falcata leaf and stem have been evaluated using GC-MS techniques. The Chemical composition of the ethanol extract of leaf and stem of D.falcata was, investigated using Perkin - Elmen has chromatography mass spectrometry. This analysis revealed the presence of Dendrophthoe falcata Dibutyl phthalate (13.26%), n- Hexadecanoic acid (13.02%), 1,3,4,5 - Tetrahydroxy-Cyclohexan (8.43%), 2,4- Imidazolidinedione, 1 – [[5-Nitro-2-(uranyl)Methylene] Amino] (6.36%), Z,E-2-Methyl-3, 13-Octadecadien-1-o1 (6.19%), Geranyl linalool Isomer-B (4.82%), Phthalic acid, 5- methylhex-2-yl butyl ester (4.28%), 1,2,3-Benzenetriol (Pyrogallol) (4.17%), 1-Octadecanol (3.99%), 9-Octadecenoic acid (Z) (3.99%), Phthalic acid, bis-(10-hydroxy decyl ester) (3.71%), 2,6,10-Trimethyl, 14-Ethylene-14-pen (3.52%), in the leaf and squalene (68.70%), 1,2-Benzenedicarboxylic acid, Diethyl ester (5.51%), 1,2-Benzenedicarboxylic acid (3.42%), 3-Methylhenicosane (3.15%), Phthalic acid, butyl oct-3-yl ester (2.42%), 2,6- Dimethylbenzenenethiol, S-(tert-butyldimethylsilyl) (1.75%), in the stem. The compounds found in the study are reported to possess antioxidants, anti-inflammatory, anticancer, cytotic, diuretic and antimicrobial activities. The results of this study offer a platform to reconfirm the properties of the components in D.falcata that are used as different ailments. Keywords: Dendrophthoe falcata, Bioactive Compounds, Dibutyl phthalate, Squalene. INTRODUCTION The plant that possess therapeutic properties or exert beneficial pharmacological effects on the animal body are generally designated as “Medicinal plants”. According to WHO consultative group on medicinal plants, “A medicinal plant is any plant which, is one or more of its organs contains substances that can be used for therapeutic purposes or which, is a precursor for synthesis of useful drugs. The constitutions of the plants are numerous in every sector of human life. [1] Many naturally occurring chemicals from plants exhibit a broad spectrum of pharmacological profile. These plant chemicals are classified as primary or secondary metabolites. The primary metabolites include the common sugars, amino acids, proteins, purines and pyrimidines of nucleic acids and chlorophyll. Secondary metabolites are the remaining plant chemicals which are produced from the primary metabolites.