International Journal of Public Health Science (IJPHS) Vol.5, No.2, June 2016, pp. 134 ~ 136 ISSN: 2252-8806 134 Journal homepage: http://iaesjournal.com/online/index.php/IJPHS Accuration of Fine Needle Aspiration Biopsy in Musculoskeletal Tumour Rahadyan Magetsari 1,2 , Hengkie Marseno 1,2 , Zikrina A. Lanodiyu 1,2 , Punto Dewo 1,2 1 Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Gadjah Mada, Indonesia 2 Dr. Sardjito General Hospital, Yogyakarta, Indonesia Article Info ABSTRACT Article history: Received Sep 16, 2015 Revised Jan 28, 2016 Accepted Mar 30, 2016 Fine needle aspiration biopsy (FNAB) has been reported to be the preferable choice of biopsy for musculoskeletal tumour. While FNAB appears to have advantages to core biopsy in the aspect of simplicity and cost, the diagnostic accuracy should be the most critical parameter in determining the choice of biopsy. This research was designed to evaluate the diagnostic accuracy of fine needle aspiration in musculoskeletal tumour in Sardjito Hospital from 2010 until 2014. This was a descriptive study from medical record in Sardjito Hospital from 2010 until 2014. The inclusion criteria are musculoskeletal tumours in all age level that has been performed FNAB with subsequent operative treatment and confirmation of histopathology examination in Sardjito Hospital. There were 41 elligible subjects in this study. Concordance diagnosis of FNAB and histopathological examination in all musculoskeletal tumor cases was found to be 86%. In addition, the concordance in soft tissue tumor cases was 94% with the detail as follows: giant cell tumor was 86%, synovial sarcoma was 50% and liposarcoma was 50%. In bone tumours, the accuracy was found to be 60% with the detail as follows: distribute osteosarcoma was 60%, osteochondroma was 50% and chondrosarcoma was 50%. Our data showed that accuracy of FNAB for diagnosis of musculoskeletal tumours was 86% with soft tissue tumour 94%, bone tumour 60% and others 93%. Therefore, Fine needle aspiration biopsy is still important diagnosis tool in musculoskeletal tumours. Keyword: Diagnostic accuracy Fine needle aspiration biopsy Histopathological examination Medical record Musculoskeletal tumor Copyright © 2016 Institute of Advanced Engineering and Science. All rights reserved. Corresponding Author: Zikrina A. Lanodiyu, Department of Orthopaedics and Traumatology, Dr Sardjito General Hospital, Jalan Kesehatan no 1 Sekip, Tel: +62 81 22 77 20 25, Fax: +62 274 55 31 43, Yogyakarta, Indonesia Email: zikrina.lanodiyu158@gmail.com 1. INTRODUCTION Oncology cases in orthopaedic department needs highly specialized resources where the gold standard for diagnosing musculoskeletal tumor is biopsy. After radiographic staging study is carried out, biopsy should be carefully planned and performed by the well-trained medical doctor. This flow can determine the correlation of radiographic and histologic findings [1]. In order to achieve proper management of those patients and prevent improper management that can lead in unnecessary amputations and mortality, long-standing recommendations suggest referring all patients that are suspected to have musculoskeletal lesions to a high-volume tertiary care centers that are capable to do biopsy and definitive treatment [2]. In the recent years, there is a paradigm shift where less invasive procedures are more preferable due to their advantages. Despite of surgical open biopsy in the diagnosis and staging phase, percutaneous biopsy using large gauge needles have gain attention in orthopaedic oncology fields. This procedures are less invasive and have lower morbidity rate compared with open biopsy. If sufficient material is successfully obtained, diagnosis can be made in 80to 98% of the cases, therefore it began to constitute the gold standard [3]. In addition, the accuracy of percutaneous biopsy to differenciate benign tumor versus sarcoma and