Open Journal of Pathology, 2018, 8, 60-67 http://www.scirp.org/journal/ojpathology ISSN Online: 2164-6783 ISSN Print: 2164-6775 DOI: 10.4236/ojpathology.2018.82007 Apr. 13, 2018 60 Open Journal of Pathology Malignant Sacrococcygeal Teratoma with Yolk Sac Differentiation in a Child—A Case Presentation Sayeeda Nasreen 1 , Mohammad Zillur Rahman 1 , Shahe Systa Mosarrat 1 , Tasnuva Sharmin 1 , Mizanur Rahman 2* 1 Department of Pathology, Chittagong Medical College, Chittagong, Bangladesh 2 Department of Biochemistry, Rangamati Medical College, Rangamati, Bangladesh Abstract Sacrococcygeal teratoma (SCT) is a common congenital neoplasm, contains derivatives of more than one of the three embryonic germ cell layers. Howev- er, malignant Sacrococcygeal Yolk Sac tumor (YST) is an extremely rare ex- tra-gonadal germ cell tumor. This case describes a two and half years old fe- male child presenting with history of swelling at sacrococcygeal region for nine months. Case was evaluated clinically. Patient’s serum alpha fetoprotein (AFP) level was elevated abnormally. FNAC of the swelling was done which shows suspicious cell for immature teratoma. Swelling excised and histopa- thological examination was carried out, the report of which shows malignant sacrococcygeal teratoma with yolk sac tumor. Keywords Sacrococcygeal Teratoma, Yolk Sac Tumor, AFP, FNAC 1. Introduction Among the Germ Cell Tumors (GCT), Sacrococcygeal teratoma (SCT) is the most common congenital neoplasm occurring with a frequency of 1 in 20,000 to 40,000 live births [1] [2], although it is also seen in adults [3]. These tumors are predominantly seen in females in a ratio of 4:1 and approximately 80% of the af- fected infants are female [4]. The majority of SCTs are benign teratomas [4]. These tumors however have the potential for malignant degeneration. Malignancy is usually limited to a sin- gle element, a yolk sac tumor (YST), also known as endodermal sinus tumor How to cite this paper: Nasreen, S., Rah- man, M.Z., Mosarrat, S.S., Sharmin, T. and Rahman, M. (2018) Malignant Sacrococcy- geal Teratoma with Yolk Sac Differentia- tion in a Child—A Case Presentation. Open Journal of Pathology, 8, 60-67. https://doi.org/10.4236/ojpathology.2018.82007 Received: January 5, 2018 Accepted: April 10, 2018 Published: April 13, 2018 Copyright © 2018 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access