Sorato et al. Clin Med Rev Case Rep 2020, 7:307
Volume 7 | Issue 5
DOI: 10.23937/2378-3656/1410307
Accepted: May 02, 2020: Published: May 04, 2020
Citaton: Sorato MM, Davari M, AbdollahiAsl A (2020) Descriptve Evaluaton of Natonal and Interna-
tonal Hypertension Treatment Guidelines: The Guideline Quality and Comprehensiveness to provide
Care to Adult with Hypertension. Clin Med Rev Case Rep 7:307. doi.org/10.23937/2378-3656/1410307
Copyright: © 2020 Sorato MM, et al. This is an open-access artcle distributed under the terms of the
Creatve Commons Atributon License, which permits unrestricted use, distributon, and reproducton
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ISSN: 2378-3656
Open Access Clinical Medical Reviews
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Sorato et al. Clin Med Rev Case Rep 2020, 7:307 • Page 1 of 14 •
Descriptve Evaluaton of Natonal and Internatonal Hyperten-
sion Treatment Guidelines: The Guideline Quality and Compre-
hensiveness to provide Care to Adult with Hypertension
Mende Mensa Sorato
*
, Majid Davari and Akbar AbdollahiAsl
Department of Pharmacoeconomics and pharmaceutcal Administraton, Faculty of Pharmacy, Tehran
University of Medical Sciences, Iran
Abstract
Background: Hypertension (Blood pressure ≥ 140/90
mmHg) is the modifable risk factor responsible for a host of
complications. Evidence based guidelines are important for
prevention and control of hypertension. However, there is
variation and inconsistencies among published guidelines
concerning, diagnosis and treatment approach. Therefore,
this review was conducted with intension to evaluatequality
and comprehensiveness of published national adult hyper-
tension treatment guideline, diagnosis and treatment ap-
proach in comparison with other national and international
guidelines.
Methods: We selected national guidelines of fve countries
(USA of America, Canada, Europe, Australia and Ethiopia)
and one international guideline.We used clinical guideline
appraisal tool to evaluate the quality of guidelines, and com-
prehensiveness of the guidelines was evaluated by using a
tool developed reach team.
Evidence synthesis: We qualitatively synthesized the ev-
idence by reviewing quality and comprehensiveness ofse-
lected guidelines.
Results: National adult hypertension treatment guideline
of Ethiopia addressed only 22 (64.7%) of quality appraisal
tool components. The guideline is least comprehensive 15
(51.7%). Major problems the guideline were; lack of diag-
nostic approach for masked, white-coat and resistant hy-
pertension; failure to address child hood risk factors and
secondary cases of hypertension. Similarly, management
of hypertension in patients undergoing surgery, specifc pa-
tient groups, access to medicine and social determinants of
health are not addressed.
Conclusion: Quality and comprehensiveness of National
hypertension guideline of Ethiopia is poor. Therefore, we
recommend the guideline development committee and oth-
er relevant stakeholders to: update the blood pressure tar-
gets for elderly population, determine when to initiate and
intensify antihypertensive drug therapy; address social de-
terminants and socioeconomic status of population includ-
ing maternal nutrition and Access of medicines.
Keywords
Hypertension treatment guidelines, Management of hyper-
tension in adults, Evidence based guideline, Ethiopia
Abbreviations
ABPM: Ambulatory Blood Pressure Monitoring; ACC/AHA:
American College of Cardiology/American Heart Associa-
tion; AGREE: Appraisal of Guidelines for Research &Eval-
uation; ASCVD: Atherosclerotic Cardiovascular Diseases;
CHD: Coronary Heart Disease; CKD: Chronic Kidney Dis-
ease; CVD: Cardiovascular Diseases; ESC/ESH: European
Society of Cardiology/European Society of Hypertension;
ESRD: End Stage Renal Disease; FGR: Fetal Growth Re-
striction; HBPM: Home Blood Pressure Monitoring; HF:
Heart Failure; JNC: Joint National Committee guideline for
management of raised blood pressure in adults; LDL-C: Low
Density Lipoprotein- Cholesterol; MI: Myocardial Infarction;
NCDs: Non-Communicable Diseases; PAD: Peripheral Ar-
terial Disease; SPC: Single Pill Combination; SPRINT:Sys-
tolic Blood Pressure Intervention Trial; TIA: Transient Isch-
emic Attack
*Corresponding author: Mende Mensa Sorato, B.Pharm, MSc. PhD scholar, Department of Pharmacoeconomics and
pharmaceutcal Administraton, Faculty of Pharmacy, Tehran University of Medical Sciences, Iran, Tel: +98-9056309138
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Background
Hypertension (Blood pressure ≥ 140/90 mmHg) is
the modifable risk factor responsible for host of compli-
catons. Startng at a blood pressure of 115/75 mmHg,