INTERNATIONAL RESEARCH JOURNAL OF ENGINEERING AND TECHNOLOGY (IRJET) E-ISSN: 2395-0056 VOLUME: 07 ISSUE: 03 | MAR 2020 WWW.IRJET.NET P-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 2110 Detection of Asthma and Diabetes from Patient Breath J. Vijaya Lakshmi 1 , S. Lakshmi Priya 2 , S. Preethi 3 and A. Divya 4 1,2,3 Final Year Students, Department of Biomedical Engineering, Alpha College of Engineering, Chennai, Tamil Nadu, India. 4 Assistant Professor, Department of Biomedical Engineering, Alpha College of Engineering, Chennai, Tamil Nadu, India. ---------------------------------------------------------------------------***---------------------------------------------------------------------- Abstract—The main purpose is to identify the diseases of people by using the breath Analysis. Breath analysis is an easier, more accurate and viable method in providing clinical care for the disease. It is a less time & low cost technique to indicate the disease. Human breath analysis offers a non- invasive and rapid method for detecting various volatile organic compounds that are indicators for different diseases. Each disease has a specific biomarker to identify the disease such as nitrous oxide for asthma, acetone for diabetes, ammonia for renal disease, sulphides for liver disease, etc.. Here, the exhalation of Breath is collected & it is detected using gas sensor. This defines the level of gas, indicates the type of disease and help the individual to monitor their disease with cheap and simple device. Keywords - breath analysis, biomarker, gas, acetone, nitrous oxide, asthma, diabetes. Abbreviations – VOC( Volatile Organic Compounds), BGL(Blood Glucose Level), LCD(Liquid Crystal Display), IoMT(Internet of Medidcal Things), NO(Nitrous Oxide). 1.INTRODUCTION The Asthma and Diabetes are the most common disease found in the old age people. Breath analysis is a non- invasive, pain free and cheap technique. Breath is the collection of highly complicated molecular matrix, the composition of nitrogen, carbon dioxide, oxygen, and water have very high percentage, which is present in our breath. Some volatile compounds are the indicators of diseases in the human. Exhaled breath analysis is a method in medicine for gaining information on the clinical state of an individual by monitoring the components present in the exhaled breath. Identification and quantification of potential disease biomarkers can be seen as the driving force for the analysis of exhaled breath .Patient with asthma have increase the level of nitric oxide in their breath, patient with renal diseases have ammonia, patient with liver diseases have sulphides in their breath, patient with diabetes have acetone in their breath, patient with cirrhosis diseases have aliphatic acid, patient with kidney failure have dimethyl amine and trimethyl amine in their breath and patient with lung cancer have substances like aldehydes, alkanes and derivatives of benzene in their breath. The breath odour exhaled from human body in the form of volatile organic compounds which can be detect and analyse by many methods like Gas chromatography and many other method for volatile organic compounds detection. Diabetes can be described as a group of metabolic diseases where the blood-glucose level in the body is higher than the normal prescribed parameter. When a person suffers from diabetes, it is seen that their body is either unable to secrete enough insulin or their body is not able to use the insulin produced by the liver. This causes sugar to build-up in the blood thus leading to diabetes[4]. Investigations show that urine, sweat, saliva, tears and breath contain traces of glucose in them, and these traces vary with the levels of glucose in the blood. Therefore, these human serums have recently gained recognition as feasible alternatives to using blood for glucose measurement. Extensive research conducted in this area concludes that human breath is a good alternative to monitor and diagnose glucose levels as acetone in the breath has shown a good correlation to BGL. It is seen that in the human breath, there are numbers of chemical compounds that relate to different diseases Traces of acetone in the breath are used for the detection of diabetes. Asthma is one of the most prevalent and costly chronic conditions[9]. It is one of the complicated state of respiratory disease which is harmful and risk in many of the people life. It cannot be cured but it can be prevented when it is treated before using the nebulizer at times. A condition in which a person's airways become inflamed, narrow and swell and produce extra mucus, which makes it difficult to breath. A common lung disorder in which inflammation causes the bronchi to swell and narrow the airways, creating breathing difficulties that may range from mild to life-threatening. In the breath analysis gas is the specific biomarker to detect each and every disease as mentioned before. Nitrous oxide is the biomarker for the Asthma. 1.1 NEED OF THE PROJECT (1)This project is used to identify the most common disease like asthma and diabetes by patients breath. (2) It is a non-invasive, cheap and a effective method. (3) It can also easily intimate the doctor in emergency situation. It overcomes the disadvantages in available device. 1.2 OBJECTIVE To analyse the exhalation of gas from breath. To correlate different gases with diseases,