~ 154 ~ The Pharma Innovation Journal 2020; SP-9(9): 154-156 ISSN (E): 2277- 7695 ISSN (P): 2349-8242 NAAS Rating: 5.03 TPI 2020; SP-9(9): 154-156 © 2020 TPI www.thepharmajournal.com Received: 18-07-2020 Accepted: 26-08-2020 Ravindrakumar Hatzade Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, Maharashtra Animal and Fishery Sciences University, Nagpur, Post Graduate Institute of Veterinary and Animal Sciences, Akola Akola, Maharashtra, India Sunil Waghmare Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, Maharashtra Animal and Fishery Sciences University, Nagpur, Post Graduate Institute of Veterinary and Animal Sciences, Akola Akola, Maharashtra, India Corresponding Author: Ravindrakumar Hatzade Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, Maharashtra Animal and Fishery Sciences University, Nagpur, Post Graduate Institute of Veterinary and Animal Sciences, Akola Akola, Maharashtra, India Therapeutic management of onion (Allium cepa) poisoning in a bullock: A case report Ravindrakumar Hatzade and Sunil Waghmare Abstract A seven year old bullock was presented to the Teaching Veterinary Clinical Complex (TVCC), Post Graduate Institute of Veterinary and Animal Sciences (PGIVAS), Akola with the complaint of passing black colour faeces, dark red urine and anorexia since last 4-5 days. History and clinical examination revealed accidental ingestion of large quantity of onions (Allium cepa), slight rise in rectal temperature (100.2 0 F), tachycardia, increased respiratory rate, pale mucous membrane, passing of black colored feces, anorexia, weakness, lethargy and staggering. The laboratory examination revealed low Hb, PCV and TEC. The case was diagnosed as an onion poisoning on the basis of history, signs, clinical examination and laboratory findings. The bullock was treated with the parenteral administration of plasma volume expander, phosphorous, vitamins and haematinics preparation. Bullock showed clinical improvement on second day and recovered completely within two weeks. Keywords: Onion poisoning, bullock, anemia, haematinics 1. Introduction The onion toxicosis in cattle may occur mainly where culled cultivated onions are inadvertently fed to livestock or where animals have accidental access to places where onions are stored [1] . Many workers reported hemolytic anemia in cattle, sheep, dogs, cats and horses caused by spontaneous ingestion of onion (Allium cepa) [2] . Severe methemoglobinemia is associated with onion toxicosis leads to cyanosis, hemolytic anemia with the formation of Heinz bodies and death [3] . The clinical signs in cattle with onion toxicosis included inappetence, staggering, abortion, onion odor of the breath and feces, elevated heart and respiratory rates, pale mucous membranes, jaundice and brown colour urine [4] . More than one toxic principle is involved in Onion-induced hemolytic anemia [5] . In the present case report a case of onion poisoning in a old bullock was successfully treated and discussed. 2. History, Clinical examination and Diagnosis A seven year old bullock from village Alegaon, Taluka Patur, district Akola, was presented to the Teaching Veterinary Clinical Complex (TVCC), Post Graduate Institute of Veterinary and Animal Sciences (PGIVAS), Akola with the complaint of passing black colour faeces, dark red colour urine and anorexia since last 4-5 days. History and clinical examination revealed accidental ingestion of large quantity of onions (Allium cepa), slight rise in rectal temperature (100.2 0 F), tachycardia on auscultation, pale mucous membranes, passing of black colored feces, dark red colour urine, anorexia, weakness, lethargy and staggering. The laboratory examination revealed low Hb (4.8 gm/dl), PCV (20.8%) and TEC (3.92/ cumm) indicated hypochromic anemia. The case was diagnosed as an onion poisoning on the basis of history, clinical examination and laboratory findings. 3. Treatment and Result In the present case, the bullock was fed excess quantity of onions, which resulted into onion toxicosis. As the animal was severe anemic and need blood transfusion. However blood transfusion could not be managed as suitable donor was not available due to COVID-19 pandemic lock down and inclusion of Akola in the red zone. The case was treated with Parenteral administration of Vetplasma (Hydroxyethyl Starch, an Plasma Volume Expander), at the dose rate of 1500 ml/day intravenously for three days, injection phosphorous (Sodium Acid Phosphate) 10 ml daily for three days, iron dextran 10 ml IM single dose, vitamins B- complex (Inj. Tribivet) 15 ml daily for 5 days, Dextrose 5% IV and haematinics preparation orally for 15 days, metronidazole at the dose rate of 10 mg/kg body weight orally for five days.