INTERNATIONAL RESEARCH JOURNAL OF ENGINEERING AND TECHNOLOGY (IRJET) E-ISSN: 2395-0056 VOLUME: 07, SPECIAL ISSUE | JUNE 2020 WWW.IRJET.NET P-ISSN: 2395-0072 International Conference on Recent Trends in Science & Technology-2020 (ICRTST - 2020) Organised by: ATME College of Engineering, Mysuru, INDIA © 2020, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 153 Effect of Incorporation of Green Synthesized ZnO Nanofillers on Mechanical and Anti-fungal Activity of PMMA Denture base Resin Green Synthesized ZnO Nanofillers for Denture Base Resin P. Shubha 1, 2 1 Department of Material Science, Mangalore University, Mangalagangotri-574199, India 2 Centre for Materials Science and Technology, Vijnan Bhavan, University of Mysore, Manasagangotri, Mysore- 570006, India K. Namratha Department of Earth Science, University of Mysore, Manasagangotri, Mysore-570006, India S. Ganesh Department Prosthodontics, Crown & Bridge, JSS Dental College and Hospital JSS AHER, SS Nagar, annimantap, Mysore -570015, India K. Byrappa Adichunchanagiri University, BG Nagara, Mandya District-571433 ---------------------------------------------------------------------***---------------------------------------------------------------------- Abstract— ZnO nanoparticles that are green synthesized using co-precipitation method and using Piper betel aqueous extract (PZnO) as bioreductant were incorporated into the powder matrix of commercially available heat cure acrylic denture base resin (PMMA) in 0.25%, 0.5% and 1% w/v ratio. PMMA specimen with/without the incorporation of PZnO nanofillers was prepared according ADA specification #12 and ISO 1567:1998 standards and tested for flexural strength, surface roughness and fungal adhesion inhibition. Mean flexural strength of PMMA standard (without PZnO nanofiller addition) was 71.285 MPa, while those incorporated with 0.25%, 0.5% and 1% PZnO showed 73. 278, 75. 886 and 72.037 MPa, respectively. Surface roughness assessment among test and control groups was statistically significant (p<0.05) with PMMA+ 1% PZnO nanofiller showing more roughness than other two groups, but less than control group. There was no statistically significant inhibition of fungal adhesion to PMMA sample surface both by test and control groups. The study concludes that PMMA with incorporation of 0.5% PZnO as nanofiller showed optimum results by the virtue of improved flexural strength and enhanced surface smoothness. Hence addition of green synthesized PZnO into PMMA matrix can be considered to augment its mechanical properties. Keywords- Polymethyl methacrylate;Green synthesized ZnO; Flexural Strength; Surface roughness 1. INTRODUCTION Conventional complete dentures still remain the treatment of choice in providing prostheses to edentulous patients and the most feasible option among rural Indian population [1]. The prime requisite of denture base material includes adequate physical and mechanical properties, esthetics and biocompatibility with oral tissues. Polymethyl methacrylate (PMMA) is one such polymeric material, which even today remains the material of choice in making dentures due to economic, medical, technical and esthetic reasons [2]. However, it is not considered an ideal material because of its inferior physical and mechanical properties and poor microbial resistance [3]. Yet another issue that is commonly faced by denture wearers is colonization of oral microbiota, especially the Candida albicans on denture surface leading to denture induced stomatitis, an inflammatory mucosal condition [4]. Earlier, studies were conducted to improve physico-mechanical properties of PMMA material, by adding macro- fillers, fibres, nanofillers and hybrid reinforcements. Metal fibres and glass fibres of different sizes were incorporated to PMMA matrix to improve transverse strength and modulus of elasticity with varying results [5]. Uniformly sized metallic nanoparticles have attracted researchers all over the world because of their excellent physical and mechanical properties, good thermal stability with added advantage of inherent antimicrobial activity