Copyright: © the author(s), publisher and licensee Technoscience Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non- commercial use, distribution, and reproduction in any medium, provided the original work is properly cited International Journal of Scientific Research in Chemistry (IJSRCH) © 2020 IJSRCH | Volume 5 | Issue 6 | ISSN : 2456-8457 1 Antifungal Activity of Malvastrum Coromandelianum Leaf Extracts Akshay R. Yadav* 1 , Pravin P. Honmane 2 , Mayuri V. Bhosale 3 , Ankita V. Chitruk 4 , Priyanka P. Rode 5 , Rushikesh M. Birajdar 6 , Manisha D. Rajput 7 , Vaibhav S. Suryawanshi 8 , Smita R. Patil 9 , Shweta S. Patil 10 , Nisha M. Jagtap 11 , Dr. Shrinivas K. Mohite 12 , Vidya N. Dange 13 , Ganesh B. Vambhurkar 14 1-12 Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Maharashtra, India 13-14 Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Maharashtra, India *Corresponding author E-mail:- akshayyadav24197@gmail.com Article Info Volume 5, Issue 6 Page Number: 01-05 Publication Issue : November-December-2020 Article History Accepted : 01 Nov 2020 Published : 15 Nov 2020 ABSTRACT Malvastrum coromandelianum belongs to the family Malvaceae, commonly known as false mallow. Ethnobotanical survey revealed that it is used to treat various disorders. A previous study discussed the anti-inflammatory activity of the M. coromandelianum ethyl acetate extract was observed by In-vitro protein denaturation method. The aim of the current study was to research possible in- vitro Malvastrum coromandelianum extracts antifungal mechanism. The antifungal role of Malvastrum coromandelianum can be confirmed by the observed results by its zone of inhibiton. Keywords: Malvastrum coromandelianum, Antifungal activity, C. albicans, A. Niger I. INTRODUCTION Herbal medicines have received more attention in recent times due to their diversity in curing diseases, safety and well-tolerated remedies compared to conventional medicines 1 . Malvastrum coromandelianum belongs to the Malvaceae family, which has been famous for its medicinal properties for many years 2 . Because of the presence of alkaloids, essential oils and phenolic quleoside the plants of this family are well known for their antibacterial and antifungal activities. Phytochemical screening of the extracts revealed the presence of alkaloids, saponins, flavonoids, triterpenes, tannins and steroids. This study aimed to investigate pharmacological properties of the extract, including antifungal action 3- 4 .Microwave extraction has proved to be more effective and efficient than its conventional counterpart, the soxhlet extraction method. The Soxhlet extraction, which is a standard technique, is a continuous solvent extraction method 5-12 . Extraction systems are used to conduct routine solvent extractions of soils, sediments, sludge, polymers and plastics, pulp and paper, biological tissues, textiles and food samples 13-26 . Experiments have proved that microwaves, in comparison with the soxhlet extraction, use a lesser volume of solvent and sample and perform extraction at a much faster rate. In the discovery of effective medicines for prevention and treatment, an outbreak of coronavirus disease (COVID-19) caused by the novel extreme acute respiratory syndrome coronavirus-2 (SARS-CoV-2)