Enteral Feeding Using Levodopa-Carbidopa
Intestinal Gel Percutaneous Endoscopic
Gastrostomy Tube
Andr eane Bernier, RD,
1
Judy Dorais, MD, FRCP(C),
2
Benoit Gagnon, RN,
1
Christiane Lepage, MD, MSc,
1
Nicolas Jodoin, MD, FRCP(C),
1
Val erie Soland, MD, FRCP(C),
1
Michel Panisset, MD, DEA, FRCP(C),
1
Sylvain Chouinard, MD, FRCP(C),
1
Antoine Duquette, MD, MSc, FRCP(C)
1,
*
In Parkinson’s disease (PD), dysphagia has a significant influence
on nutritional status.
1
When dysphagia is resistant to oral nutri-
tion intervention, enteral nutrition using a percutaneous endo-
scopic gastrostomy (PEG) can be considered.
2
A levodopa (L-DOPA)-carbidopa intestinal gel (LCIG) has
been used to treat advanced PD using a PEG with a jejunal exten-
sion (PEG-J) (AbbVie, Montr eal, Canada). We present a case in
which the LCIG PEG-J was used successfully for feeding.
Case Description
A 71-year-old man treated with LCIG was referred because he
suffered from recurring aspiration pneumonia. A swallowing
evaluation showed moderate oro-pharyngeal dysphagia. Despite
modified food textures, food enrichment, supplementation, and
appropriate nutrition counseling, the patient experienced mod-
erate-to-severe malnutrition.
Enteral nutrition was initiated using a 15-Fr (5-mm) LCIG
PEG-J through the gastric port. Nutrition was first adminis-
tered with a feeding pump during the night while infusion of
LCIG was stopped. To complement his nutritional intake, he
received two boluses during the day. After a few weeks, as a
result of sleeping discomfort, a new isocaloric enteral nutrition
plan was established. Five boluses were administered with the
feeding pump simultaneously with LCIG to mimic usual meal
times.
FIGURE 1 An adaptor had to be crafted to ensure compatibility between the gastric port of the LCIG PEG-J tube and the enteral nutrition tube.
A: Standard PEG connection. B: LCIG PEG-J adapted for enteral nutrition (20 Fr PEG-J is required to allow for administration of medication).
1
Service de Neurologie du D epartement de M edecine,Unit e des Troubles du Mouvement Andr e-Barbeau, Centre Hospitalier de l’Universit e de
Montr eal, Montr eal, Canada;
2
Service de Gastro-ent erologie du D epartement de M edecine, Centre Hospitalier de l’Universit e de Montr eal, Montr eal,
Canada
*Correspondence to: Dr. Antoine Duquette, Unit e des Troubles du Mouvement Andr e-Barbeau, Service de Neurologie du D epartement de
M edecine, Centre Hospitalier de l’Universit e de Montr eal, 1560 rue Sherbrooke Est (GR-1177), Montr eal, Qu ebec, Canada; E-mail: antoine.
duquette@umontreal.ca
Keywords: Duodopa, dysphagia, enteral nutrition, gastrostomy, intestinal gel, Parkinson’s disease.
Relevant disclosures and conflicts of interest are listed at the end of this article.
Received 14 November 2016; revised 21 February 2017; accepted 8 March 2017.
Published online 5 May 2017 in Wiley InterScience (www.interscience.wiley.com). DOI:10.1002/mdc3.12490
© 2017 International Parkinson and Movement Disorder Society
787
doi:10.1002/mdc3.12490
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