Extracorporeal membrane oxygenation–assisted primary percutaneous coronary intervention may improve survival of patients with acute myocardial infarction complicated by profound cardiogenic shock ☆,☆☆ Nai-Wen Tsao MD a , Chun-Ming Shih MD, PhD b,c , Jong-Shiuan Yeh MD d , Yung-Ta Kao MD c , Ming-Hsiung Hsieh MD d , Keng-Liang Ou PhD e , Jaw-Wen Chen MD f , Kou-Gi Shyu MD, PhD g , Zen-Chung Weng MD a , Nen-Chung Chang MD, PhD b,c , Feng-Yen Lin PhD b,c,e, ⁎ , Chun-Yao Huang MD b,c,e,g, ⁎ a Division of Cardiovascular surgery, Department of Surgery, Taipei Medical University Hospital, Taipei 11031, Taiwan b Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan c Division of Cardiology, Department of Internal Medicine, Taipei Medical University hospital, Taipei 11031, Taiwan d Division of Cardiology, Taipei Medical University-Wan Fang Hospital, Taipei 11031, Taiwan e Biomedical Apparatus Research Center, Taipei Medical University, Taipei 11031, Taiwan f Division of Cardiology, Taipei Veterans General Hospital, Taipei 11031, Taiwan g Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan Keywords: Acute myocardial infarction; Cardiogenic shock; Extracorporeal membrane oxygenation; Percutaneous coronary intervention Abstract Purpose: The aim of this study was to evaluate the impact of extracorporeal membrane oxygenation (ECMO) assistance on the clinical outcome of patients with acute myocardial infarction (AMI) that is complicated by profound cardiogenic shock (CS) who received primary percutaneous coronary intervention (PCI). Materials and Methods: We collected patients from January 2004 through December 2006 (stage 1); 25 patients who presented with AMI and received primary PCI and had profound CS were enrolled in the study. Intraaortic balloon counterpulsation (IABP) was the only modality for extracorporeal support in our hospital. From January 2007 through December 2009 (stage 2), 33 patients who presented with AMI and received primary PCI and had profound CS were enrolled; for this stage; both intra-aortic balloon counter-pulsation and ECMO support were available in our facility. ☆ Financial support: The study was partially supported by the grant of National Science Council (NSC 99-2314-B-038-007-MY3) and Taipei Medical University (TMU 99-AE1-B23), Taiwan. ☆☆ Disclosure: None declared. ⁎ Corresponding authors. Tel.: +886 2 27372181x3903; fax: +882 2 27363051. E-mail addresses: g870905@tmu.edu.tw (F.-Y. Lin), cyhuang@tmu.edu.tw (C.-Y. Huang). 0883-9441/$ – see front matter © 2012 Elsevier Inc. All rights reserved. http://dx.doi.org/10.1016/j.jcrc.2012.02.012 Journal of Critical Care (2012) 27, 530.e1–530.e11