Sah et al Journal of Drug Delivery & Therapeutics. 2019; 9(1):202-206
ISSN: 2250-1177 [202] CODEN (USA): JDDTAO
Available online on 15.01.2019 at http://jddtonline.info
Journal of Drug Delivery and Therapeutics
Open Access to Pharmaceutical and Medical Research
© 2011-18, publisher and licensee JDDT, This is an Open Access article which permits unrestricted
non-commercial use, provided the original work is properly cited
Open Access Research Article
Occurrence of anemia among the people of Gurugram, Haryana: a cross
sectional study
Ashok Kumar Sah
*
and Rajesh Prasad Jayaswal
Department of Medical Laboratory Technology, Amity Medical School, Amity University Haryana, India
ABSTRACT
Anemia is considered a condition, not a disease in which numbers of red blood cells (RBCs) are insufficient to meet the body’s metabolical and
physiological needs for oxygen. Anemia may also develop due to nutritional deficiencies such as iron, vitamin B12, folic acid, and vitamin A;
moderate and severe inflammation; parasitic infestation; and acquired or inherited disorders that affect hemoglobin synthesis, red blood cell
development or red blood cell endurance. This proposed work depicts the distribution of different morphological types of anemia on people of
Gurugram, Haryana. All the samples were analyzed for CBC and peripheral blood smear by using Sysmax (three parts) hematology analyzer and
microscopy. In the present study, 300 patients in 6 months study period were included to diagnose anemia. Only 166 cases were positive. Out of
166 cases, 85 (51.2%) were female and 81 (48.8%) were male. The highest number of participants showed RBCs count in the range of 4.5-5.5
million/mm
3
, 24 (14.5%) with P value 0.000. Most of the cases that we revealed were having hypochromic red cells along with morphological
variation in RBCs which may be due to iron deficiency. The further confirmatory analysis may be required in order to know the detail
classification of anemia.
Keywords: Anemia, Hemoglobin, Iron Deficiency, Hypochromic, Red Blood Cells
Article Info: Received 28 Nov 2018; Review Completed 06 Jan 2019; Accepted 09 Jan 2019; Available online 15 Jan 2019
Cite this article as:
Sah AK, Jayaswal RP, Occurrence of anemia among the people of Gurugram, Haryana: a cross sectional study, Journal of
Drug Delivery and Therapeutics. 2019; 9(1):202-206 DOI: http://dx.doi.org/10.22270/jddt.v9i1.2288
*Address for Correspondence:
Ashok Kumar Sah, Amity Medical School, Amity University Haryana, India.
INTRODUCTION
Anemia is a global health issues affecting both male and
female of all age groups. In such condition, the body is
incapable to meet the need for oxygen through the limited
number of red cells. This need varies individual to individual
due to variation in gender, age, environment (altitude),
smoking habits, and also during different stages of
pregnancy. Iron deficiency is thought to be the most common
cause of anemia globally. In addition, anemia may also
develop due to other nutritional deficiencies such as vitamin
B12, folic acid, and vitamin A; moderate and severe
inflammation; parasitic infestation; and acquired or
inherited disorders that affect hemoglobin synthesis, red
blood cell development or red blood cell endurance.
Anemia is a condition, not a disease, but it is the reflection of
underlying diseases and from the treatment point of view, it
is essential to identify the etiology of anemia. The definition
of anemia is as a decrease in the number of red blood cells or
the decreased percentage of hemoglobin in the blood
1
. It can
also be termed as a reduction of more than 10% of the
normal value of a total number of red blood cells, the amount
of circulating hemoglobin and RBC mass of a particular
individual
2
. Formally anemia is said to be decreasing in RBC,
hemoglobin, and hematocrit below the previously
established normal values for healthy persons of the same
age, gender, and race and under similar environmental
conditions. Its diagnosis is made from the signs and
symptoms, physical examination, history, hemoglobin level
and other procedures and findings
3
.
According to WHO, anemia is defined as if hemoglobin level
less than 11 g/dl for children below six years and less than
12 g/dl for children more than six years of age and a report
shows that 52.0% of pregnancies and around 35.0 to 40.0%
of women are anemic in developing countries due to iron
deficiency
4-6
. The situation in Nepal is more severe where
36.0% cases have been recorded in age group of 15 to 49 in
which 42.0% pregnant and 40.0% lactating women have
been reported as anemic
7
. A few studies carried out among
adolescent girls in Nepal reported that prevalence ranges
from 42 to 60.0%
8, 9
.
Morphologically anemia can be classified as microcytic
hypochromic anemia which characteristically shows reduced
MCV (mean corpuscular volume) values (<80fl) as well as
reduced MCHC (mean corpuscular hemoglobin
concentration) values (30gm/dl), normocytic normochromic
which has normal MCV (82-100 fl) values, macrocytic
hypochromic anemia which shows characteristic increased
MCV values (>100fl) and normal MCHC. The etiological
method of classification involves anemias due to impaired