Molecular thermodiffusion (thermophoresis) in liquid mixtures Semen N. Semenov 1 and Martin E. Schimpf 2 1 Institute of Biochemical Physics RAS, 117977 Moscow, Kosygin Street 4, Russia 2 Department of Chemistry, Boise State University, Boise, Idaho 83725, USA Received 20 April 2005; published 18 October 2005 Thermodiffusion thermophoresisin liquid mixtures is theoretically examined using a hydrodynamic ap- proach. Thermodiffusion is related to the local temperature-induced pressure gradient in the liquid layer surrounding the selected molecule and to the secondary macroscopic pressure gradient established in the system. The local pressure gradient is produced by excess pressure due to the asymmetry of interactions with surrounding molecules in a nonuniform temperature field. The secondary pressure gradient is considered an independent parameter related to the concentration gradient formed by volume forces, calculated from the generalized equations for mass transfer. Values of Soret coefficients for mixtures of toluene and n-hexane are calculated using parameters in the literature. When the molecules are assumed to be similar in shape, the calculated Soret coefficients are lower than the empirical values found in the literature. However, by introduc- ing an asymmetry parameter, which is calculated from independent measurements of component diffusion in the literature, very good agreement is obtained. DOI: 10.1103/PhysRevE.72.041202 PACS numbers: 66.10.Cb I. BACKGROUND When a liquid mixture is placed in a temperature gradient, there is movement of the constituent components, generating a concentration gradient. This coupling between temperature and concentration gradients is known as thermodiffusion or the Ludwig-Soret effect. Since its discovery by Ludwig 1 and the first systematic investigations of thermodiffusion in liquid mixtures by Soret 2, the effect has been subject to numerous experimental and theoretical studies. Investiga- tions of the Ludwig-Soret effect in liquid mixtures typically involve measurements of a so-called thermal diffusion coef- ficient, an ordinary massdiffusion coefficient, or a ratio of the two that is referred to as the Soret coefficient. Tools used to measure the Soret coefficient in liquid mixtures include the thermogravitational column 3and thermal field-flow fractionation TFFF4. Thermal diffusion coefficients are measured by forced Rayleigh scattering TDFRS5and beam deflection methods 6. A variety of techniques are used to measure mass diffusion coefficients, including TDFRS and dynamic light scattering 7. Data provided by these methods have been used to compare values obtained by molecular dynamic MDsimulations 8,9. A summary of the information obtained by these methods can be found in Refs. 10,11. TFFF has proven to be particularly adept at measuring the Soret coefficients of dissolved polymers and suspended particles. In one of the more comprehensive studies on polymer thermodiffusion 12by TFFF, the independence of thermodiffusion on chain length and branching configura- tion was demonstrated, as predicted by scaling considerations 13,14. In a later study of polymers 15dissolved in binary solvent mixtures, the dependence of thermodiffusion on the relative concentration of solvent components in specific mixtures was found to be nonlinear. The curvature in these relationships, which can be either positive or negative, provides evidence for the existence of multiple forces affecting the thermodiffusion of dissolved solutes in liquid mixtures. The independence of polymer thermodiffusion on chain length and branching configuration means that the polymer chain moves at the same velocity as that of the individual monomer units mers, at least for homopolymers. Therefore, we have modeled polymer thermodiffusion using a similar approach as that used for particle thermophoresis 16. This hydrodynamic approach, which has been used to explain the thermodiffusion of hydrophobic homopolymers in pure sol- vents 17, considers the molecules surrounding a selected mer as a continuous medium, while the selected mer is con- sidered a solid particle suspended in that medium. The flow of liquid around the particle is caused by a local pressure gradient in the surface layer of the particle, as defined by the Navier-Stokes equation u =- loc + f loc , 1 where u is the velocity of the liquid, loc is the local pressure distribution around the particle due to its interaction with molecules of the liquid, is the dynamic viscosity of the liquid, and f loc is any local volume force in the liquid around the particle. In a temperature or concentration gradi- ent, the local pressure distribution is not uniform due to asymmetry in the distribution of molecules around the particle. The same asymmetry also causes a local volume force on the particle. The validity of this approach does not depend on the size of the particle, provided the size is com- parable or larger than the solvent molecules, because the model is based on the hydrodynamic motion of liquid in the layer surrounding the particle. However, the model’s validity does depend on the frequency of intermolecular collisions being great enough to consider the solvent as a continuous medium. PHYSICAL REVIEW E 72, 041202 2005 1539-3755/2005/724/0412029/$23.00 ©2005 The American Physical Society 041202-1