Case Report
Hypertrophic Cardiomyopathy and Wolff-Parkinson-White
Syndrome in a Young African Soldier with Recurrent Syncope
Mohammed Abdullahi Talle ,
1,2
Faruk Buba,
1,2
Aimé Bonny ,
3
and Musa Mohammed Baba
1,4
1
Department of Medicine, College of Medical Sciences, University of Maiduguri, Nigeria
2
Cardiology Unit, Department of Medicine, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria
3
University of Douala, Cameroon
4
Cardiology Unit, Department of Medicine, College of Medical Sciences, Gombe State University, Gombe, Nigeria
Correspondence should be addressed to Mohammed Abdullahi Talle; abdultalle@yahoo.com
Received 28 July 2019; Accepted 25 November 2019; Published 4 December 2019
Academic Editor: Kathleen Ngu
Copyright © 2019 Mohammed Abdullahi Talle et al. This is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
is properly cited.
Syncope is a common manifestation of both hypertrophic cardiomyopathy (HCM) and Wolff-Parkinson-White (WPW) syndrome.
The most common arrhythmia in HCM is ventricular tachycardia (VT) and atrial fibrillation (AF). While preexcitation provides the
substrate for reentry and supraventricular tachycardia (SVT), AF is more common in patients with preexcitation than the general
population. Concurrence of HCM and WPW has been reported in many cases, but whether the prognosis or severity of
arrhythmia is different compared to the individual disorders remains unsettled. We report a case of HCM and Wolff-Parkinson-
White (WPW) syndrome in a 28-year-old male Nigerian soldier presenting with recurrent syncope and lichen planus.
1. Introduction
Inherited cardiac arrhythmogenic disorders are less reported
in Africa, and their burden as causes of sudden cardiac death
(SCD) in Africa is unknown [1]. The lack of the often-
needed expensive state-of-the-art diagnostic equipment
compounds the challenges that hinder establishing the epi-
demiology of cardiac arrhythmias in sub-Saharan African
(SSA) countries [2]. This makes the reporting of every single
case of clinical arrhythmia (symptomatic or otherwise)
imperative, to aid in better understanding of the burden of
arrhythmic cardiac disorders in SSA.
Concurrence of HCM and WPW has been variously
reported. In a consecutive series of patients presenting with
preexcitation, 7.62% were found to have HCM [3]. Of the
many phenocopies of HCM, cardiac hypertrophy and preexci-
tation are typically caused by a mutation of the gamma 2 sub-
unit of the adenosine monophosphate-activated protein
kinase (PRKAG2) [4]. Although both HCM and WPW are
independently associated with various forms of arrhythmias
and SCD, whether their concurrence will result in more
frequent and severe arrhythmias or fatalities remains con-
jectural, and to our knowledge, this has not been reported
in SSA. We present a case of HCM with WPW in a young
African soldier presenting with recurrent syncope.
2. Case Presentation
A 28-year-old male African soldier from Nigeria was referred
to the cardiology clinic of the University of Maiduguri Teach-
ing Hospital in November 2017 for evaluation of recurrent
syncope. He complained of paroxysmal palpitations, dizziness,
and shortness of breath followed by presyncope and syncope.
He has had subtle and infrequent palpitation and shortness of
breath since childhood. He experienced his first syncope about
2 years ago which became more frequent three months prior
to his referral and has had about 10 episodes of syncope.
The last episode was in November 2017, during which a heart
rate of 184 beats per minute and blood pressure of
90/50 mmHg with cold clammy extremities were documented
by the attending medical officer at a peripheral hospital.
Hindawi
Case Reports in Cardiology
Volume 2019, Article ID 1061065, 5 pages
https://doi.org/10.1155/2019/1061065