_____________________________________________________________________________________________________ *Corresponding author: E-mail: pateras@uniwa.gr; Ophthalmology Research: An International Journal 13(4): 1-9, 2020; Article no.OR.61476 ISSN: 2321-7227 Comparison of Central Corneal Thickness Measurements between Angiovue Optical Coherence Tomography, Ultrasound Pachymetry and Ocular Biometry E. Pateras 1* and A. I. Kouroupaki 2 1 Biomedical Department, Course of Optics and Optometry, University of West Attica, Athens, Greece. 2 Biomedical Department, Course of Optics and Optometry, Greece. Authors’ contributions This work was carried out in collaboration between both authors. Author EP designed the study, wrote the protocol, and managed the literature searches. Author AIK wrote the first draft of the manuscript, performed the statistical analysis and managed the analyses of the study. Both authors read and approved the final manuscript. Article Information DOI: 10.9734/OR/2020/v13i430172 Editor(s): (1) Dr. Tatsuya Mimura, Tokyo Women's Medical University Medical Center East, Japan. Reviewers: (1) Ankur Sharma, Sher-e-Kashmir University of Agricultural Sciences & Technology of Jammu, India. (2) Mridula V. Amarnath, Chinmaya Mission Hospital, India. Complete Peer review History: http://www.sdiarticle4.com/review-history/61476 Received 15 July 2020 Accepted 20 September 2020 Published 02 October 2020 ABSTRACT Purpose: To compare central corneal thickness (CCT) measurements and their reproducibility when taken by Ultrasound Pachymetry, Ocular Biometry and Angiovue Optical Coherence Tomography (OCT). Methods: Twenty-five healthy volunteers were recruited creating a sample size of 50 eyes. All subjects had pachymetric measurements by Ultrasound pachymetry (PachPen Handheld Pachymeter, Keeler Instruments Inc), Ocular biometry (IOL Master 700 Swept Source Biometry, Zeiss) and Angiovue Optical Coherence Tomography (Optovue Avanti RTVue XR Angiovue). The measurements of central corneal thickness for the three devices were taken by the same examiner twice for more accuracy. Results: The average measurements of central corneal thickness by Ultrasound pachymetry (PachPen Handheld Pachymeter, Keeler Instruments Inc), Ocular biometry (IOL Master 700 Swept Source Biometry, Zeiss) and Angiovue Optical Coherence Tomography (Optovue Avanti RTVue XR Original Research Article