Frontiers in Health Informatics www.ijmi.ir 2020; 9: 31 Open Access Copyright© 2019, Published by Frontiers in Health Informatics. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY) License (http://creativecommons.org/). TECHNICAL REQUIREMENT OF CLINICAL DECISION SUPPORT SYSTEM FOR DIABETIC PATIENTS Shamim Kiyani 1 , Sanaz Abasi 1 , Zahra Koohjani 1 , Azam Aslani 2 1 Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran. 2 PhD in Medical Informatics, National Agency for Strategic Research in Medical Education, Tehran, Iran. Article Info A B S T R A C T Article type: Review Introduction: Diabetes is a public health problem which is originating an increment in the demand for health services. There is an obvious gap exists between actual clinical practice and optimal patient care, clinical decision support systems (CDSSs) have been promoted as a promising approach that targets safe and effective diabetes management. The purpose of this article is reviewing diabetes decision support systems based on system design metrics, type and purpose of decision support systems. Material and Methods: The literature search was performed in peer reviewed journals indexed in PubMed by keywords such as medical decision making, clinical decision support systems, Reminder systems, diabetes, interface, interaction, information to 2019. This article review the diabetes decision support systems based on system design metrics (interface, interaction, and information), type and purpose of decision support system. Results: 32 of the 35 articles were decision support systems that provided specific warnings, reminders, a set of physician guidelines, or other recommendations for direct action. The most important decisions of the systems were support for blood glucose control and insulin dose adjustment, as well as 13 warning and reminder articles. Of the 35 articles, there were 21 user interface items (such as simplicity, readability, font sizes and so on), 23 interaction items (such as Fit, use selection tools, facilitate ease of use and so on) and 31 item information items (such as Content guidance, diagnostic support and concise and so on). Conclusion: This study identified important aspects of designing decision support system, It can be applied not only to diabetic patients but also to other decision support systems. Most decision support systems take into account a number of design criteria; system designers can look at design aspects to improve the efficiency of these systems. Decision support system evaluation models can also be added to the factors under consideration. Keywords: Diabetes Mellitus, Decision Support Systems, Clinical Article History: Received: 2020-03-30 Accepted: 2020-04-25 Published: 2020-05-03 * Corresponding author: Azam Aslani PhD in Medical Informatics, National Agency for Strategic Research in Medical Education, Tehran, Iran. Email: a.aslani@nasrme.ac.ir How to cite this paper Kiyani S, Abasi S, Koohjani Z, Aslani A. Technical Requirement of Clinical Decision Support System for Diabetic Patients. Front Health Inform. 2020; 9: 31. DOI: 10.30699/fhi.v9i1.217 INTRODUCTION Diabetes prevalence is increasing all over the world due to sociocultural changes (the global prevalence of worldwide diabetes is around 9%) [1]. It is becoming a public health problem which is originating an increment in the demand for health services [2]. Diabetes mellitus is one of the most common systemic diseases in the world and it occurs when the pancreas does not produce enough insulin or when the body cannot effectively use that insulin [3]. It is classified into two main types: Type 1 (previously known as insulin-dependent) diabetes and type 2 (formerly known as non-insulin- dependent) diabetes [3]. However, many diabetic