IOSR Journal of Nursing and Health Science (IOSR-JNHS) e-ISSN: 2320–1959.p- ISSN: 2320–1940 Volume 6, Issue 4 Ver. I (Jul. - Aug. 2017), PP 22-28 www.iosrjournals.org DOI: 10.9790/1959-0604012228 www.iosrjournals.org 22 | Page Establishment of Cerebral Palsy Research Registry in North Cairo Egypt Marian N. Shawky 1 , Samah A. El Shemy 2 , Faten H. Abdelazeim 3 1 Physical Therapist in Shubra General Hospital, Egypt 2 Assistant Professor in Department of Physical Therapy for Pediatrics, Faculty of Physical Therapy, Cairo University, Egypt 3 Professor and Head of Department of Physical Therapy for Pediatrics, Faculty of Physical Therapy, Cairo University, Egypt Abstract Background: Cerebral palsy is the most common neurodevelopmental motor disability in children. There is a lack of information concerning the predominance of cerebral palsy among Egyptian children. Cerebral palsy registry appears to be appropriate tools for answering questions regarding the prevalence and the attributes of the disorder. Aim: To establish a registry of cerebral palsy in North Cairo, Egypt. Subjects: 184 children with cerebral palsy of both genders with age ranged from 3 months to 18 years participated in this study. They selected from hospitals and private centers in North Cairo. Methods: Gross Motor Function Classification System (GMFCS), Manual Ability Classification System (MACS) and Viking Speech Scale (VSS) used for assessment. Results: The results revealed that the boy/ girl ratio was 1.3/1. Spastic CP was the most common type representing 90.3%. Moreover, the spastic quadriplegic type representing 54.9%. According to GMFM, MACS, VSS level V and IV had the highest percentage respectively. Conclusion: Prevalence of CP was more in boys than girls. Spastic CP was the most common type with high incidence of quadriplegia. In addition, hypoxia was the most common risk factor for CP. Furthermore, there were significant relations between types of CP and gestational age, epilepsy, intellectual impairment, GMFCS, MACS and VSS findings. Keywords: Cerebral palsy, Registry, North Cairo. I. Introduction Cerebral palsy (CP) is a group of permanent movement disorders that appear early in life. Signs and manifestations vary among children and incorporate spasticity, poor coordination and muscle weakness. Other associated disorders incorporate seizures, cognitive problems, sensory deficits as well as hearing, vision, speech and swallowing problems [1] . Prevalence of cerebral palsy is around 2.1 per 1,000 live births. It caused by damage to the parts of the developing brain responsible for movement control, balance, and posture. Frequently the issues happen during pregnancy; however, they may also occur during childbirth, or shortly after birth. The conceivable reasons for CP incorporate issues in intrauterine development as exposure to radiation, hypoxia of the brain, trauma occurred during labor and delivery, and post neonatal factors such as head trauma or cerebral infections [2,3] .Cerebral palsy classified according to muscle tone disturbance into three types including; spastic, ataxic, and athetoid types. Additionally, there is a mixed type that demonstrates a combination of features of the other three types and hypotonic type that show decrease in muscle tone. Spastic subtype classified according to the topographic distribution of muscle spasticity as diplegia, hemiplegia or quadriplegia. Athetoid (or dyskinetic) CP essentially associated with damage to the basal ganglia during brain development due to bilirubin encephalopathy and hypoxic ischemic brain injury. Ataxic CP is the least frequent form of CP and observed in 5-10% of all cases of CP. Ataxic CP brought about by damage to cerebellar structures. Children with ataxic CP experience issues in coordination, particularly in their arms, legs, and trunk [4] . Cerebral palsy research registry created to identify the disparity between population and clinical-based cerebral palsy registries and promote research in the field. This accomplished by interfacing people with CP, as well as their families, to a network of regional specialists. The registry, or core data project, consists of multiple sub cores that have specialty specific related data per patient. Cerebral palsy registries have a remarkable position to help with deciding etiological comprehension and counteractive actions by utilizing the framework of multiple causal pathways to CP. This aim concentrates on the potential for CP registries to increase awareness of CP among community and professional groups through publications, support and interactive multimedia [5] . Therefore, the purpose of the current study was to recognize the prevalence and the disability profile of CP cases from referral centers of physiotherapy and rehabilitation in North Cairo, Egypt.