Int.J.Curr.Microbiol.App.Sci (2019) 8(7): 1272-1278 1272 Review Article https://doi.org/10.20546/ijcmas.2019.807.151 Quorum Sensing and Its Applications in Diverse Fields of Significance Malik Asif Aziz 1* , Shazia Lone 2 , Mushtaq Ah. Malik 1 , Zaffar Mahdi Dar 1 , Amjad Masood 3 , Misbah Aijaz 1 , Saima Shafi 1 and Showkat Sidique 4 1 Division of Basic Sciences & Humanities, Faculty of Agriculture, Wadura (J&K)-India 2 Department of Environmental Sci. Govt Degree College, Kupwara (J & K) -India 3 Division of Agronomy, Faculty of Agriculture, Wadura (J&K)-India 4 Division of Statistic, Faculty of Agriculture, Wadura (J&K)-India *Corresponding author ABSTRACT Introduction Engineered QS-based circuits have a broad range of applications such as production of biochemical‟s, tissue engineering, also mixed- species fermentations. They are also extremely useful in designing microbial biosensors to identify bacterial species present in the environment and inside living organisms. A decade ago, the secretion and perception of minor signalling molecules that in turn are transduced to coordinate behaviour of a „smallest unit‟ of microorganisms was named quorum sensing by EP Greenberg with colleagues. Ever since then, an exponential growth in understanding and occurrence of quorum- sensing systems has developed, with sightings ranging from virulence inhuman along with plant pathogens to degradative capacity of activated sludge. Advance characterization of signalling circuits, coupled with creative position applications, propose a wealth of prospects International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 8 Number 07 (2019) Journal homepage: http://www.ijcmas.com Several unicellular microorganisms use small signalling molecules to find out their local concentration. The processes involved in the production and recognition of these signals are generally known as quorum sensing (QS). Unicellular microorganisms to manage their activities use this kind of cell- to-cell communication, which allows them to work as multi-cellular systems. Newly, several groups have confirmed artificial intra species and inter-species communication through synthetic circuits, which incorporate components of bacterial QS systems. Keywords Quorum sensing and applications Accepted: 12 June 2019 Available Online: 10 July 2019 Article Info