Indian Research Journal of Pharmacy and Science; T. A. Al-Refai et. al. June’17 (Suppl) Ind Res J Pharm & Sci|2017: June.: 4 (2)Suppl. 1031 STUDYING THE EFFECT OF ASPIRIN TREATMENT ON DIABETIC NEUROPATHY AMONG DIABETIC PATIENTS ATTENDING JORDANIAN ROYAL MEDICAL CITY Taghreed A. Al-Refai 1 , Raeda Abdel Wahab Al Madadha 1 , Ala'AldeenTaha Salem Alfaqara 1 , Bayan Ahmad Althwaib 1 , Reem Ibrahim Mahadeen 1 , Fadi Jamal AlNimri 1 , Jaafar AbuAbeeleh 1 , Ahed J Alkhatib 2, 3* 1 Royal Medical Services, Jordan 2 Department of legal medicine, Toxicology of Forensic Science and Toxicology, School of Medicine, Jordan University of Science and Technology, Jordan 3 Council for Nutritional and Environmental Medicine, Mo i Rana, Norway ABSTRACT: Introduction: Diabetes is associated with the involvement of defects in the nervous system which leads to diabetic neuropathy. Treatment with aspirin has been associated with improvement of several diseases. Objectives: To study the impact of using aspirin treatment on diabetic neuropathy. Methodology: This is a retrospective study. Files of diabetic patients were reviewed. Files were included if neuropathy is involved and aspirin treatment is indicated. Data were gathered from files of patients visiting internal medicine outclinics at royal medical services. Study variables included gender, age, diabetic duration, aspirin treatment, and diabetic neuropathy. The data was entered into working excel sheets and once completed were analyzed using SPSS version 20. Several statistical analyses were included such as frequency, percentage, mean, standard deviation, Chi-square, and T-test. Significance was accepted at alpha level <0.05. Results: The findings of the present study showed that the prevalence of diabetic neuropathy was 25.8%. The mean age of diabetic patients was 56.95±11.97 years. Half of patients were reported to use aspirin treatment. The mean of duration diabetes was 7.51±5.86 years. The mean of aspirin dose was 111.37±24.67 mg. Males were more likely to develop diabetic neuropathy compared with females, but this was not statistically significant (p>0.05). Patients using aspirin treatment were less likely to develop diabetic neuropathy, but this was not statistically significant (p>0.05). Conclusion: Although it was not statistically significant, male were more likely to develop diabetic neuropath, whereas aspirin using patients were less likely to develop diabetic neuropathy. KEYWORDS: Diabetes, Diabetic neuropathy, Aspirin, Aspirin dose. Corresponding Author: Jaafar Abu Abeeleh Tel: 00962772047577 E-mail address: ayhamjafar@yahoo.com Submitted on: 30.05.17; Revised on: 08.06.17; Accepted on: 10.06.17 ORIGINAL RESEARCH Indian Research Journal of Pharmacy and Science; 13(2017)1009-1014; Journal Home Page: https://www.irjps.in DOI: 10.21276/irjps.2017.4.2.11