Author’s Reply
Response to Editorial Comment to Use of sigmoid colon in orthotopic neobladder
reconstruction: Long-term results
We thank Dr Abe for the opportunity to focus on some
aspects of our article.
1
Our index of early complications depends above all on a
studied selection of candidates. As we had stated, just
19.1% of cystectomy patients receive a sigmoid neobladder.
Any candidate not in optimal health with severe comorbidi-
ties was excluded, as noted in the text.
2
Regarding postop-
erative management, all patients are admitted to a recovery
room until they are fully awake, then they are admitted to
subintensive care (or intensive care when required) until
normal bowel function resumes. They receive parenteral
hypercaloric nutrition during the first few postoperative
days. Another protective factor could be surgical constancy
– all patients were operated on by the same two experi-
enced surgeons.
Regarding pouch perforation, we have encountered this
problem only once and it did not represent a life-threatening
scenario. The patient was managed conservatively, with
neobladder catheterization for 5 weeks. In fact, the thick sig-
moidal wall probably prevents perforation.
We agree that follow up of these patients never ends, it
continues until death because in the long term, changes in
their body can alter organ functionality and metabolism. In
reality, we never interrupt contact with our patients.
Regarding continence, we underline that no consensus on
the definition of continence in patients who have undergone
neobladder reconstruction has been formulated, and this fact
impacts standards in reported data.
Our continence standards are stringent: the definition of
continence signifies no pads or condom devices during the
day and at night. Furthermore, patients who carry out clean
intermittent catheterization are separated from the continent
group into a category of their own. We recognize them as
having a distinct functional outcome.
Therefore, had we counted as continent patients who carry
out clean intermittent catheterization or use up to two pads/
day (as do some authors
3
) our continence rates would have
been higher.
Giulio Nicita M.D.,
1
Alberto Martini M.D.,
1
Maria Teresa Filocamo M.D.,
2
Calogero Saieva M.D.,
3
Aldo Tosto M.D.,
1
Niceta Stomaci M.D.,
1
Barbara Bigazzi M.D.
1
and Donata Villari M.D.
1
1
Department of Urology, Careggi Hospital, University of
Florence, Florence,
2
Department of Urology, Azienda
Sanitaria Locale Cn1, Savigliano, and
3
Molecular and
Nutritional Epidemiology Unit, Cancer Research and
Prevention Institute, Florence, Italy
gnicita@unifi.it
DOI: 10.1111/iju.13230
Conflict of interest
None declared.
References
1 Abe T. Editorial comment to use of sigmoid colon in orthotopic neobladder
reconstruction: Long-term results. Int. J. Urol. 2016; 23: 990.
2 Nicita G, Martini A, Filocamo MT et al. Use of sigmoid colon in ortho-
topic neobladder reconstruction: Long-term results. Int. J. Urol. 2016; 23:
984–90.
3 Hautmann RE, de Petriconi R, Gottfried HW, Kleinschmidt K, Mattes R, Paiss
T. The ileal neobladder: complications and functional results in 363 patients
after 11 years of followup. J. Urol. 1999; 161: 422–7.
© 2016 The Japanese Urological Association 991
Long-term results of the sigmoid neobladder