28 Lumaksono, et al. • pISSN: 2085-1545 • eISSN: 2339-093X http://jurnal.unissula.ac.id/index.php/sainsmedika Sains Medika, Vol. 8, No. 1, January - June 2017 : 28-33 Death in Patients with Regular Hemodialysis Due to CKD in RSUD Dr. Soedono Madiun Not Correlated to Various Risk Factors Tulus Lumaksono 1* , Anisa Rachmawati 2 , Erlina Marfianti 3 1 Department of Medicine Hospital Madiun dr.Soedono 2.3 Lecturer at the Faculty of Medicine, Universitas Islam Indonesia 1 tlumaksono@yahoo.com ; 2 anisa.rachma.dr@gmail.com, 3 erlyna_marf@yahoo.com ABSTRAK Pendahuluan: Pasien yang menjalani hemodialisa secara regular akibat Chronic Kidney Disease (CKD) mengalami peningkatan risiko kematian dalam 2 dekade terakhir. Berbagai faktor risiko yang diangap berpengaruh antara lain umur, jenis kelamin, lama menjalani hemodialisis, durasi hemodialisis, dan komorbid yang menyertai penderita. Tujuan: Untuk mengidentifikasi faktor risiko kematian penderita Chronic Kidney Disease (CKD) yang menjalani hemodialisa regular. Metode: Jenis penelitian observasional dengan desain case-control. Penelitian di lakukan di RSUD dr.Soedono Madiun, jumlah sampel sebanyak 41 pada kelompok kasus dan 41 kelompok kontrol. Data diambil melalui rekam medis pasien CKD yang menjalani HD regular di bulan Januari-November 2016. Analisis data menggunakan uji odd ratio dengan CI 95%, tingkat signifikansi 5% (α=0,05). Hasil: Tidak terdapat hubungan yang bermakna antara usia (p=0,23; OR=1,78; CI 95% 0,68 – 4,64), jenis kelamin (p=0,623; OR=1,24; CI 95% 0,49-3,18), lama menjalani HD (p=0,12; OR=0,50; CI 95% 0,20 - 1,20), durasi HD (p=0,81, OR=0,89; CI 95% 0,34 – 2,28), hipertensi (p=0,21; OR= 0,44; CI 95% 0,12 – 1,61), diabetes mellitus (p=0,17; OR=1,83; CI 95% 0,75 – 4,47), kadar Hb (p=0,26; OR=1,66; CI 95% 0,68 – 4,05) dan komplikasi intradialitik (p=0,81, OR=1,11; CI 95% 0,44 – 2,80) dengan kematian pada penderita yang menjalani hemodialisi akibat CKD. Kesimpulan: Tidak terdapat hubungan yang bermakna antara usia, jenis kelamin, lama menjalani hemodialisa, durasi HD, hipertensi, DM, Hb, dan komplikasi intradialitik dengan kematian pada penderita HEMODIALISIS AKIBAT CKD di RSUD dr.Soedono Madiun. Kata Kunci: risiko, kematian, CKD, hemodialisa, regular Abstract Introduction: Patients undergoing regular hemodialysis due to Chronic Kidney Disease (CKD) have an increased risk of death in the last 2 decades. Various risk factors are considered to be influential such as age, sex, length of hemodialysis, duration of hemodialysis, and comorbid accompanying the patient. Objective: To identify risk factors for mortality sufferers of Chronic Kidney Disease (CKD) undergoing regular hemodialysis. Methods: observational study with case-control design. The research was conducted in RSUD dr.Soedono Madiun, the number of samples counted 41 in case group and 41 control group. Data retrieved through the medical records of patients with CKD who underwent regular HD from January to November 2016. Data analysis used were odds ratios with 95% CI, 5% significance level (α = 0.05). Results: There were no significant correlations between age (p = 0.23; OR = 1.78, 95% CI 0.68 to 4.64), gender (p = 0.623; OR = 1.24; CI 95% 0.49 to 3.18), long live HD (p = 0.12; OR = 0.50, 95% CI 0.20 to 1.20), duration of HD (p = 0.81, OR = 0, 89, 95% CI 0.34 to 2.28), hypertension (p = 0.21; OR = 0.44, 95% CI 0.12 to 1.61), diabetes mellitus (p = 0.17; OR = 1.83; 95% CI 0.75 - 4.47), Hb levels (p = 0.26; OR = 1.66; 95% CI 0.68 - 4.05) and intradialitic complications (p = 0, 81, OR = 1,11; 95% CI 0.44 - 2.80) with death in patients undergoing hemodialysis due to CKD. Conclusion: There is no significant correlations between age, gender, length of hemodialysis, duration of HD, hypertension, diabetes, hemoglobin, and complications intradialytic with mortality in hemodialysis patients with CKD in RSUD dr.Soedono Madiun. Keywords: risk, mortality, CKD, hemodialysis, regular INTRODUCTION Declining kidney can cause patients with kidney failure to fall in the stage of end-stage renal failure. End stage renal disease is the terminal stage of Chronic Kidney Disease (CKD) indicated by the inability of the kidneys in maintaining homeostasis of the body. This resulted in the patient should undergo lifelong renal replacement therapy (hemodialysis) (Ignatavicius & Workman, 2006). In the last 2 decades patients who undergo regular hemodialysis have a higher risk of death than ever before. Various observations suggest that the survival rate of the patients who received hemodialysis varies, influenced by several factors, including age, sex, and duration of hemodialysis. The low survival rate of patients undergoing hemodialysis due to CKD can be caused by inadequate hemodialysis and other factors such as nutritional status, psychosocial and comorbid status (Widiyatmoko, 2009). Among patients Copyright @ 2017 Authors. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial- ShareAlike 4.0 International License (http://creativecommons.org/licenses/by-nc-sa/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are properly cited. RESEARCH ARTICLE