Quest Journals Journal of Medical and Dental Science Research Volume 8~ Issue 7 (2021) pp: 18-22 ISSN(Online) : 2394-076X ISSN (Print):2394-0751 www.questjournals.org *Corresponding Author: Rhita Bennis Nechba 18 | Page Research Paper The burden of managing anticoagulants in old patients suffering from coronavirus disease 2019. A case report and review of the literature. Rhita Bennis Nechba 1,2 , Jihane Belayachi 1,2,3 , Naoufel Madani 1,2,3 , Redouane Abouqal 1,2,3 1 Acute Medical Unit, Ibn Sina University Hospital, 10000, Rabat, Morocco 2 Mohammed V University, 10000, Rabat, Morocco 3 Laboratory of Biostatistics, Clincial, and EpidemiologicalResearch, Faculty of medecine and pharmacy- Mohamed V University Souissi, 10000, Rabat, Morocco Corresponding author: Rhita Bennis Nechba at Acute Medical Unit, Ibn Sina University Hospital, 10000, Rabat, Morocco, Abstract : Background: Old patients are at risk of experiencing adverse drug events. The risk of morbidity and mortality enhances especially in cases of acute infections. Controversy exists regarding the potential of anticoagulation to reduce mortality and incidence of thrombo embolic events in coronavirus disease 2019 patients. In addition, prescription of anticoagulation is not without its risks of bleeding and must be optimized on geriatric population. Case report : We report a case of a 80-years old female who presented a Severe Acute Respiratory Syndrome- coronavirus 2. We discuss throught this case The burden of managing anticoagulants in old patients suffering from Severe Acute Respiratory Syndrome-coronavirus 2. Conclusion : prescription of anticoagulants must be optimized on geriatric population because health care delivery is not infallible. More researchs are needed to improve the outcome of old patients suffering from Severe Acute Respiratory Syndrome-coronavirus 2. Keywords: old patients, anticoagulants, coronavirus disease 2019, Acute Medical Unit. Received 06 July, 2021; Revised: 18 July, 2021; Accepted 20 July, 2021 © The author(s) 2021. Published with open access at www.questjournals.org I. BACKGROUND : Since the end of 2019, the Severe Acute Respiratory Syndrome-coronavirus 2 (SARS-Cov-2) pandemic exposes old patients to the risk of early death [1]. Even if the pandemic started several months ago, the management of severe disease still difficult and new discoveries appear ofen. One of the most common clinical findings in SARS-Cov-2 patients is the occurrence of Both venous and arterial thrombotic complications leading to poorer outcomes [2,3]. Controversy exists regarding the potential of anticoagulation to reduce mortality and incidence of thrombo embolic events in coronavirus disease 2019 (COVID-19) patients [3]. It is well known that anticoagulation is not without its risks of bleeding and is therefore a therapy that requires close clinical monitoring. The majority of bleeding events were reported to be on therapeutic anticoagulation [4]. We use a clinical case to discuss the difficulty of managing anticoagulants in a 80-year-old woman suffering from SARS- Cov-2. II. PRESENTATION OF CASE : A 80-year-old woman was admitted to our Acute Medical Unit because of confusion and dyspnea during the pandemic of COVID-19.She was oriented and did not had any cognitive disorders before. The patient did not took any drugs at home.She was frail, not autonomous, undernourished, had a low weight 50 Kg with pressure ulcer and a severe form of COVID-19. Her temperature was 37°C. Her respiratory rate was 28 breaths per minute, the oxygen saturation was 69 % while she was breathing ambient air and 94% while the patient was receiving supplemental oxygen through a reservoir mask at a rate of 15 liters per minute. Her blood pressure