Research Article
Numerical Simulation of Nonlinear Pulsatile Newtonian
Blood Flow through a Multiple Stenosed Artery
Satyasaran Changdar
1
and Soumen De
2
1
Institute of Engineering & Management, Saltlake, Kolkata 700101, India
2
Department of Applied Mathematics, University of Calcutta, 92 Acharya Prafulla Chandra Road, Kolkata 700009, India
Correspondence should be addressed to Satyasaran Changdar; satyasaran.changdar@iemcal.com
Received 16 July 2015; Accepted 13 October 2015
Academic Editor: Abdelouahed Tounsi
Copyright © 2015 S. Changdar and S. De. Tis is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
cited.
An appropriate nonlinear blood fow model under the infuence of periodic body acceleration through a multiple stenosed artery
is investigated with the help of fnite diference method. Te arterial segment is simulated by a cylindrical tube flled with a viscous
incompressible Newtonian fuid described by the Navier-Stokes equation. Te nonlinear equation is solved numerically with the
proper boundary conditions and pressure gradient that arise from the normal functioning of the heart. Results are discussed in
comparison with the existing models.
1. Introduction
At present the investigation of blood fow analysis in a
stenosed artery is very important in the medical domain
because of the fact that many of the diseases such as heart
attacks and strokes are related to blood fow and the physical
characteristic of vessel wall. Nowadays the leading causes
of the death in the world are due to heart diseases such as
atherosclerosis. Atherosclerosis involves an accumulation of
low-density lipoprotein in the wall of large arteries, typically
where the wall shear rate is low and oscillatory [1].
Investigation of blood fow modeling through arterial
multistenosis is very challenging. Accuracy of the simulation
depends mainly on suitable numerical approach, realistic
model geometry, and boundary conditions. Many investi-
gators have focused their attention on blood fow through
stenosed arteries with single stenosis by Mekheimer [2, 3],
Chakravarty and Mandal [4], Lee and Xu [5], who pointed out
that the mathematical model becomes more accurate in the
presence of an overlapping stenosis instead of a mild one. Ang
and Mazumdar [6] studied asymmetric arterial blood fow
with numerical solution in three dimensions, and Ikbal et
al. [7] have worked on unsteady response of non-Newtonian
blood fow in magnetic feld without considering periodic
body acceleration. Khler et al. [8] studied the wall shear
stress with the help of magnetic resonance imaging (MRI)
measurements of the velocity feld and compared them with
simulation outputs. Stroud et al. [9] have studied a 2D plaque
model using modeling and simulation while Fischer et al. [10]
worked on numerical method for the computational study of
arterial blood fow with turbulence. Te asymmetric fows in
a symmetric sudden expansion channel have been studied
using experimental and numerical techniques by Fearn et
al. [11] and Durst et al. [12]. Mahapatra et al. [13] investi-
gated unsteady laminar separated fow through constricted
channel using fnite diference technique in staggered grid
distribution and suggested that the critical value of Reynolds
number depends on the area reduction and the length of
the constriction. Chakravarty and Sannigrahi [14] solved
blood fow model with body acceleration but they do not
consider the nonlinear terms in the model. Blood shows
a non-Newtonian behaviour at low shear rates in tubes of
smaller diameters, and Taylor [15] suggested that at high shear
rates commonly found in larger arteries blood behaves like a
Newtonian fuid.
Hindawi Publishing Corporation
International Scholarly Research Notices
Volume 2015, Article ID 628605, 10 pages
http://dx.doi.org/10.1155/2015/628605