MIDDLE EAST JOURNAL OF FAMILY MEDICINE • VOLUME 7, ISSUE 10 47 ORIGINAL CONTRIBUTION/CLINICAL INVESTIGATION WORLD FAMILY MEDICINE/MIDDLE EAST JOURNAL OF FAMILY MEDICINE VOLUME 16 ISSUE 3, MARCH 2018 Evaluation of the Effect of Aloe Vera Ointment with Chamomile Ointment on Severity of Children’s Diaper Dermatitis: A randomized, double-blind clinical trial Sima Ghanipour Badelbuu (1) Yousef Javadzadeh (2) Mahnaz Jabraeili (3) Shiva Heidari (4) Mohammad Arshadi Bostanabad (5) (1) MSc Student in Pediatric Nursing, Student Research Committee , Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran (2) Professor, Department of Pharmaceutics and Biotechnology Research Center, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran (3) PhD Candidate, Department of Pediatric Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran (4)MS in Nursing, Faculty of Nursing and Midwifery school, Urmia Islamic Azad University, Urmia, Iran (5) PhD, Assistant Professor, Department of Pediatric Nursing, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran Corresponding Author: Mohammad Arshadi Bostanabad Department of Pediatric Nursing, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran Email: arshadi_m@yahoo.com Received: December 25, 2017; Accepted: December 30, 2017; Published: March 1, 2018. Citation: Sima Ghanipour Badelbuu et al. Evaluation of the Effect of Aloe Vera Ointment with Chamomile Ointment on Severity of Children’s Diaper Dermatitis: A randomized, double-blind clinical trial. World Family Medicine. 2018; 16(3):47-51. DOI: 10.5742/MEWFM.2018.93304 Abstract Introduction: Diaper dermatitis is an infammation of the skin under the diapers of children, and is relatively common. The disease is seen in children and adolescents with a degree of urinary inconti- nence. The aim of this study is to replace uncom- plicated herbal medicines in the treatment of this disease instead of chemical drugs. Materials and Methods: This is a randomized, dou- ble-blind, clinical trial that was performed on 90 children under 2 years of age who were referred to the Pediatric Department of Tabriz Pediatric Hos- pital and who used diapers. The children were ran- domly divided into three groups of 30, and formed a routine group and two other groups, with rou- tine ointment and chamomile and Aloe Vera Oint- ment. Sampling was performed on the frst, third and sixth days of the study using a fve point scale. Data were analyzed using SPSS software (version 22) and descriptive and analytical statistics. Results: According to the statistical results, the severity of dermatitis in all three groups improved during the study on the sixth day compared to the frst day, but there was no signifcant difference in the severity of diaper dermatitis between the three groups during the study period. (P> 0.05) Conclusion: Regarding the treatment process in all three groups and having positive results in the treatment of dermatitis, the three groups of drugs were effective in treatment, but they were not su- perior to each other. But due to the lower side effects of herbal medi- cine, its use is recommended to treat this condi- tion. Key words: Aloe vera ointment, chamomile ointment, diaper dermatitis