Case Report
Dry Gangrene in Children with Typhoid Intestinal Perforation:
A Report of Two Cases
Lofty-John C. Anyanwu ,
1
Aminu M. Mohammad,
1
Lawal B. Abdullahi,
1
Mustapha U. Ibrahim,
2
Aliyu U. Farinyaro,
1
Mohammed S. Aliyu,
1
and Stephen K. Obaro
3,4,5
1
Paediatric Surgery Unit, Department of Surgery, Aminu Kano Teaching Hospital, Bayero University Kano, Nigeria
2
Orthopaedic Surgery Unit, Department of Surgery, Aminu Kano Teaching Hospital, Bayero University Kano, Nigeria
3
Department of Paediatrics, Aminu Kano Teaching Hospital, Kano., Nigeria
4
International Foundation Against Infectious Diseases in Nigeria (IFAIN), Nigeria
5
Division of Pediatrics Infectious Disease, University of Nebraska Medical Center, Omaha, USA
Correspondence should be addressed to Lofty-John C. Anyanwu; loftyjohnc@yahoo.com
Received 7 April 2018; Accepted 23 September 2018; Published 8 October 2018
Academic Editor: Gregorio Santori
Copyright © 2018 Lofty-John C. Anyanwu et al. This is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Intestinal perforation is a life-threatening complication of typhoid fever commonly seen in developing countries, but extraintestinal
complications are infrequently reported. We report herein two cases of gangrene seen in children managed for typhoid intestinal
perforation, highlighting the challenges faced in their management.
1. Introduction
Salmonella enterica serovar Typhi, the causative organism in
typhoid fever, is a gram-negative facultative anaerobic bacte-
ria which commonly causes intestinal and systemic patholo-
gies in the host [1]. Injuries caused by this organism on the
intestinal mucosa result in the systemic translocation of the
organism and other intestinal microbiota and may result in
intestinal perforation [2]. Being a systemic pathogen, a num-
ber of complications have been described in infected patients,
although cases of gangrene are rarely reported [3–9]. We
include in this report two cases of gangrene seen in children
managed for typhoid intestinal perforation in our unit.
2. Case Presentation
2.1. Case 1. A 9-year-old girl was presented to our hospital on
referral from a peripheral hospital with a one-week history of
darkish discoloration of both feet and her left hand and a
six-day history of a purulent feculent discharge from an
exploratory laparotomy wound. She had presented to the
referring hospital eight days earlier, with a two-week history
of high-grade fever and a one-week history of a generalized
abdominal pain and diarrhea. She had an exploratory lapa-
rotomy at the referring hospital. Intraoperative findings
include a feculent intraperitoneal collection and a single per-
foration on the antimesenteric border of the terminal ileum.
An intraoperative diagnosis of perforated typhoid enteritis
was made, and the perforation was closed in two layers.
One unit of blood was transfused postoperatively. On the
first day of postsurgery, the patient developed darkish discol-
oration of the left hand and both feet which were associated
with pain. She was not a known sickle cell disease patient
and had no past histories suggestive of intermittent claudica-
tion. On the second day of postoperation, a purulent dis-
charge from the lower aspect of the laparotomy wound was
noted, and there was darkening of the feet and duskiness of
the distal one-third of both legs. Due to the progressive
worsening of the patient’s condition, she was referred to
our hospital on the seventh day of postoperation.
At presentation to our unit, she was acutely ill looking,
febrile with a temperature of 38.1
°
C, dehydrated, not pale,
and anicteric. Her respiratory rate was 30/minute with
reduced air entry and coarse crepitations in both lower lung
fields. She had a pulse rate of 130/minute, which was regular
and of moderate volume. Only first and second heart sounds
Hindawi
Case Reports in Surgery
Volume 2018, Article ID 7097014, 4 pages
https://doi.org/10.1155/2018/7097014