Health Notions, Volume 4 Number 6 (June 2020) ISSN 2580-4936 180 | Publisher: Humanistic Network for Science and Technology DOI: http://dx.doi.org/10.33846/hn40604 http://heanoti.com/index.php/hn RESEARCH ARTICLE URL of this article: http://heanoti.com/index.php/hn/article/view/hn40604 Comparison of Sarcopenia Diagnostic Component Between Two Age Groups in Men Yahya Taqiuddin Robbani 1(CA) , Novira Widajanti 2 , Nuniek Nugraheni Sulistiawaty 3 1(CA) Medicine Program, Faculty of Medicine, Universitas Airlangga, Indonesia; yahya.taqiuddin.robbani@gmail.com (Corresponding Author) 2 Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga / Dr. Soetomo General Hospital Surabaya, Indonesia; novirawidajanti@fk.unair.ac.id 3 Department of Physical and Rehabilitation Medicine, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Hospital Surabaya, Indonesia; nuniek.nugraheni@fk.unair.ac.id ABSTRACT Sarcopenia is a condition which characterized by loss of muscle mass, muscle strength and muscle function due to aging. Some study found that sarcopenia prevalence was more common in men than women. This study aims to determine the comparison of sarcopenia diagnostic component between two group ages in men by observing and comparing muscle mass, handgrip strength and usual gait speed according to Asian Working Group on Sarcopenia (AWGS) diagnostic criteria that analyzed by Independent Sample T Test. The sample size with consecutive sampling technique was 149 mens which divided into two groups based on ages of elderly over 60 years (n = 73) and young adult between 18-40 years (n = 76). From the independent sample t test results, there was significant difference of muscle mass mean, handgrip strength mean and gait speed mean between elderly group and young adult group by 2.467 (SD ± 0.1454) kg/m 2 (t(98.350) = -16.969; p = 0.000), 10.455 (SD ± 1.0983) kg (t(147) = -9.519; p = 0.000) and 0.4753 (SD ± 0.2808) m/s (t(11.636) = -16.747; p = 0.000) which means along with increasing age, sarcopenia diagnostic components value, i.e. muscle mass, muscle strength, and physical performance will also decrease. Keywords: sarcopenia; bioelectric impedance analysis; handgrip strength; gait speed; AWGS INTRODUCTION Physical ability and performance will decrease along with age, increasing risk of several harmful health problems such as falling, fracture, disability, decreased quality of life, hospitalization and death (1) . This condition is characterized by progressive decrease of skeletal muscle mass and function known as sarcopenia (2) . Sarcopenia is a condition characterized by loss of muscle mass, muscle strength and muscle function disorder due to aging process (1),(2) . It was first mentioned by Irwin Rosenberg in 1989 to explain the loss of muscle mass along with age (3) . The newest definition was published by European Working Group of Sarcopenia (EWGSOP) in 2010 whereas inserting changes of muscle function and muscle weakness following decreased muscle mass (2) . Sarcopenia can be caused by neurodegenerative process, inadequate nutrition, disuse situation, pro- inflammatory cytokines such as IL-1, IL-6, and TNF-α, and endocrinopathy which causes abnormal thyroid function, increased cortisol, insulin resistance, and decreased anabolic hormone level such as GH, IGF-1, vitamin D and testosterone and estrogen (3) . Several studies also found that sarcopenia was more dominant in male compare to female (4),(5),(6) . Currently, the operational definition and diagnostic strategy of sarcopenia in Asia is based on Asian Working Group for Sarcopenia (AWGS) consensus modified from European Working Group on Sarcopenia in Older People (EWGSOP) (7),(8) . AWGS recommended the use of two low muscle mass and low muscle function (strength or performance) for the diagnosis of sarcopenia. Diagnosis of sarcopenia according to AWGS and EWGSOP requires the measurement of muscle mass by DXA or bioelectric impedance analysis, muscle strength measurement using handgrip strength and physical performance using usual gait speed test (2),(5),(7),(8) . The cut-off value recommended by AWGS was 7.0 kg/m 2 in male and 5.7 kg/m 2 in female for muscle mass measured using bioelectric impedance analysis defined as appendicular skeletal muscle mass/height 2 , 26 kg in male and 18 kg in female for handgrip strength and 0.8 m/s for gait speed (7),(8) . EWGSOP divided sarcopenia into three levels, i.e. pre-sarcopenia, sarcopenia and severe sarcopenia (1) . Pre-sarcopenia is characterized by decreased muscle mass without any effect on muscle strength or physical