Glo. J. Pharm. All. Sci., Volume 1 (Issue 5), September – October 2020; Article No. 01, Pages: 1-7 ISSN: 2582-5909 Peer-reviewed, Open Access, Bi-monthly Published, International Journal, for Pharma and Allied Sciences Available online at www.journalforpharma.com ©Copyright protected. Unauthorised republication, reproduction, distribution, dissemination and copying of this document in whole or in part is strictly prohibited. 1 . Global Journal for Pharma and Allied Sciences QUICK RESPONSE CODE Review Article DOI: 10.47583/gjfpas.2020.v01i05.001 DOI URL: http://dx.doi.org/10.47583/gjfpas.2020.v01i05.001 Oral Thin Film: Advanced Oral Dosage Form Jayshree Mankar*, Dr. Dinesh Biyani, Dr. Milind Umekar Department of Pharmaceutics, SKB college of Pharmacy, Kamptee, Dist. Nagpur, Pin 441002, India. *Corresponding author’s E-mail: jayshreemankar9@gmail.com Received on: 06-06-2020; Revised on: 18-08-2020; Accepted on: 22-08-2020; Published on: 25-09-2020 ABSTRACT Fast dissolving oral films (FDOFs) are the most advanced form of oral solid dosage form due to more flexibility and comfort. It improves the efficacy of APIs by dissolving within minute in oral cavity after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water for administration. some patients, particularly pediatric and geriatric patients, have difficulty in swallowing or chewing solid dosage forms. Many pediatric and geriatric patients are unwilling to take these solid preparations due to fear of choking. Hence orally dissolving tablets have come into existence. The OTFs place as an alternative in the market due to consumer’s preference for a fast-dissolving product over conventional tablets / capsules. Keywords: Fast dissolving oral film, solid dosage form, efficacy of APIs. INTRODUCTION ral route is most preferred route by medical practitioners and manufacturer due to highest acceptability of patients. Many pharmaceutical dosages are administered in the form of pills, granules, powders, and liquids. Generally, a pill design is for swallowing intact or chewing to deliver a precise dosage of medication to patients. However, some patients, particularly pediatric and geriatric patients, have difficulty in swallowing or chewing solid dosage forms. Many pediatric and geriatric patients are unwilling to take solid preparations due to fear of choking. Hence orally dissolving tablets have come into existence. Even with these differences, most of the existing oral dissolving drug delivery systems are in the form of solid tablets are designed to dissolve/disintegrate in the patient's mouth without the need to drink or chew. However, the fear of taking solid tablets and the risk of choking for certain patient populations still exists despite their short disintegration/dissolution times. Hence oral film drug delivery is a better alternative in such cases. The OTF place as an alternative in the market due to consumer’s preference for a fast-dissolving product over conventional tablets / capsules. The oral thin-film technology is still in the beginning stages and has bright future ahead because it fulfils all the need of patients. Oral Thin Film OTF also known as or dispersible film by the European Medicines Agency have attracted significant research and acceptance recently. The idea of OTFs was first presented in the 1970s to overcome swallowing difficulties that the traditional dosage forms like capsules and tablets exhibited. Normal oral flora comprises a diverse array of organisms which includes eubacteria, archaea, fungi, mycoplasmas and protozoa. Among these, fungi are classified as eukaryotes, and the most important to dentistry belong to the genus Candida. Human infections caused by Candida albicans and other related species range from the more common oral thrush to fatal, systemic superinfections in patients who are afflicted with other diseases. Pseudomembranous candidiasis is the most commonly recognized type of candidiasis and is also known as thrush. It is seen more often in immunocompromised individuals, in such conditions patient has difficulty in swallowing hence oral thin film is suitable approach. O