International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 08 Issue: 04 | Apr 2021 www.irjet.net p-ISSN: 2395-0072 © 2021, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 3460 Benefits of Papaya Fruit and its leaves to Treat Malaria or Dengue and Various Other Uses for Human Health Meesha Deshpande (Guide) 1 , Prashant Singh Parihar 2 , Shibani Brahma 3 , Aditi Shirole 4 , Eesha Vahikar 5 , Harshita Agarwal 6 1-6 Symbiosis Skill and Professional University (Kiwale), Pune. -------------------------------------------------------------------------***------------------------------------------------------------------------ Abstract: The tropical fruit Papaya is loaded with Vitamins A, B, C, D and E, fiber as well as healthy plant components. It also contains papain enzyme which is used to tenderize meat and which also aids the digestion process. The antioxidants present may help reduce the oxidative stress and thereby lower risks of other diseases. Adding to that, it may also help against sun damage and defend wrinkling of the skin. Papaya is delicious when eaten ripe, alone or it can also be easily combined with other foods. Papaya has several health benefits, previous studies have shown the plant extract effectiveness in the treatment of malaria and dengue. Not only the fruit is beneficial but also the extracted papaya leaf juice has antimalarial properties and is beneficial in increasing the platelets count, which can be done naturally rather than depending on any medications for the same. It has several properties such as anti-wrinkle,anti-inflammatory, anti-cancer, which help in maintaining optimum health. Furthermore, the papaya fruit is also highly effective for healthy skin with anti-wrinkle, anti-acne properties. Currently it is a popular remedy for treating Melasma. It has beneficial effects on the hair such as hair conditioning, hair growth and dandruff prevention for healthy scalp and hair. Papaya consumption during PMS or menstruation cycle should be restricted due to its thermogenic effect on the body, portion control is important to avoid any adverse effects. Consumption of green or unripe papaya should be highly avoided during pregnancy or breastfeeding as it may be harmful for the fetus or the infant. Moreover, in the recent future,papaya in the form of capsules may be used for therapeutic treatments or as an ingredient within the range of skin and hair care products. Keywords: papain, leaf extract, meat tenderizer, acne control, allergy, chymopapain, antimalarial, dengue, platelets. Introduction: Papaya fruit is from the plant Carica papaya, originated in Central America and Southern Mexico but it is now grown in most of the other parts of the world. When unripe the skin is green and orange when ripe with the flesh being yellow, orange or red. It also has many black seeds, edible but bitter. This fruit contains papain enzyme which helps break down the tough chains of protein in the muscle meat and hence for thousands of years it has been used as a meat tenderizer. The leaf extract has antimalarial properties and is highly effective in increasing the platelets count; observed to be beneficial in patients suffering from malaria and dengue respectively. Not only internally, but externally as well it has shown effects on the skin making it radiant, clear, acne free and on the hair making them dandruff free. A medium sized papaya (approximately 275g) contains ● Energy – 119 kcal ● Protein – 1.3 g ● Carbohydrates – 30g ● Fat – less than 1g