1 Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia Authors: Xiaowei Zhu 1,2 , Bo Zhou 1,2 , Reenal Pattni 1,2 , Kelly Gleason 3 , Chunfeng Tan 3 , Agnieszka Kalinowski 1 , Steven Sloan 4 , Anna-Sophie Fiston-Lavier 5 , Jessica Mariani 6 , Brain Somatic Mosaicism Network ‡ , Alexej Abyzov 7 , Dimitri Petrov 8 , Ben A. Barres 9† , Hannes Vogel 10 , John V. Moran 11,12 , Flora M. Vaccarino 6,13 , Carol A. Tamminga 3 , Douglas F. Levinson 1 , Alexander E. Urban 1,2* Affiliations: 1 Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 2 Department of Genetics, Stanford University, Palo Alto, CA 3 Division of Translational Research in Schizophrenia, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 4 Department of Human Genetics, Emory University, Atlanta, GA 5 Institut des Sciences de l'Evolution de Montpellier (UMR 5554, CNRS-UM-IRD-EPHE), Université de Montpellier, Place Eugène Bataillon, Montpellier, France 6 Child Study Center, Yale University, New Haven, CT 7 Department of Health Sciences Research, Mayo Clinic, Rochester, MN 8 Department of Biology, Stanford University, Palo Alto, CA 9 Department of Neurobiology, Stanford University, Palo Alto, CA 10 Department of Pathology, Stanford University, Palo Alto, CA 11 Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 12 Department of Internal Medicine, University of Michigan, Ann Arbor, MI 13 Department of Neuroscience, Yale School of Medicine, New Haven, CT . CC-BY-NC-ND 4.0 International license certified by peer review) is the author/funder. It is made available under a The copyright holder for this preprint (which was not this version posted June 10, 2019. . https://doi.org/10.1101/660779 doi: bioRxiv preprint