Am J Psychiatry 165:11, November 2008 1407 Images in Psychiatry ajp.psychiatryonline.org Paul Eugen Bleuler and the Birth of Schizophrenia (1908) T he term “schizophrenia” was coined 100 years ago, on April 24, 1908, when Paul Eugen Bleuler gave a lecture at a meeting of the German Psychiatric Association in Berlin (1): “For the sake of further discussion I wish to emphasize that in Kraepelin’s demen- tia praecox it is neither a question of an essential dementia nor of a necessary precociousness. For this reason, and because from the expression dementia praecox one cannot form further adjec- tives nor substantives, I am taking the liberty of employing the word schizophrenia for revising the Kraepelinian concept. In my opinion the breaking up or splitting of psychic functioning is an excellent symptom of the whole group” (2). Kraepelin’s use of “dementia” derived from the Latin word mens and the prefix de-, expressing privation; it was a noun that implied a static condition. While Kraepelin selected descriptions of the symp- toms and studied their time course mostly from patients’ records, Bleuler collected material directly from his passionate clinical work. By accommodating himself to the spatial and temporal environ- ment of his patients, he realized that the condition was not a single disease (he referred to a “whole group” of schizophrenias [3]), was not invariably incurable, and did not always progress to full demen- tia, nor did it always and only occur in young people. The main symptoms of this disease were the loosening of associations, distur- bances of affectivity, ambivalence, and autism (“the four A’s”) (4). However, the splitting of different psychological functions, resulting in a loss of unity of the personality, was the most important sign of disease in Bleuler’s conception (4). Thus, he challenged the ac- cepted wisdom of the time and advanced his purportedly less static and stigmatizing concept by juxtaposing the Greek roots schizen (σχι ´ ζειν, “to split”) and phre ¯n, phren- (ϕρη ´ ν, ϕρεν-, originally de- noting “diaphragm” but later changing, by metonymy, to “soul, spirit, mind”). After completing his studies in medicine (1881) and mental and nervous diseases (1883), Bleuler visited Paris, London, and Munich. He became director of a small psychiatric clinic situated in an abandoned monastery on the Rhine (Rheinau, 1886–1898), then he was appointed professor and director of the Burghölzli Asylum in Zurich (1898–1927). Among his pupils there were such outstanding personalities as Carl Gustav Jung, Karl Abraham, Eu- gene Minkowski, Ludwig Biswanger, and Hermann Rorschach. He published the work “Dementia praecox oder Gruppe der Schizophrenien” in 1911 (3) and the book Lehrbuch der Psychiat- rie in 1916 (5). He died in 1939 in Zollikon, Switzerland, where he had been born in 1857. References 1. Bleuler E: Die Prognose der Dementia praecox (Schizophre- niegruppe). Allgemeine Zeitschrift für Psychiatrie und psych- ischgerichtliche Medizin 1908; 65:436–464 2. Kuhn R (translated by Cahn CH): Eugen Bleuler’s concepts of psychopathology. Hist Psychiatry 2004; 15:361–366 3. Bleuler E: Dementia Praecox or the Group of Schizophrenias (1911). Translated by Zinkin J. New York, International Univer- sities Press, 1950 4. Stotz-Ingenlath G: Epistemological aspects of Eugen Bleuler’s conception of schizophrenia in 1911. Med Health Care Philos 2000; 3:153–159 5. Bleuler E: Lehrbuch der Psychiatrie. Berlin, Springer, 1916 PAOLO FUSAR-POLI, M.D. PIERLUIGI POLITI, M.D., PH.D. Address correspondence and reprint requests to Dr. Fusar-Poli, Department of Applied and Psychobehavioral Health Sciences, University of Pavia, via Bassi 21, 27100 Pavia, Italy; p.fusar@libero.it (e-mail). Photograph reproduced by permission of Civic Library of Cremona, Italy. Image ac- cepted for publication June 2008 (doi: 10.1176/appi.ajp.2008.08050714). View publication stats View publication stats