vv Archive of Biomedical Science and Engineering DOI CC By 003 Engineering Group Citation: Priya GV, Mallikarjuna Rao T, Ganga Rao B (2016) Antibacterial Activity of Borassus Flabellifer. Biomed Sci Eng 1(1): 003-005. DOI: http://dx.doi.org/10.17352/abse.000006 http://dx.doi.org/10.17352/abse.000006 DOI Abstract Background: The present study was carried out to evaluate the antibacterial properties of different extracts of Borassus flabellifer belonging to the family Arecaceae, which has been using to treat different illnesses. Methods: The root part was selected for the antibacterial activity and different extracts were prepared using soxhlet extraction procedure using different solvents successively and those were tested for their antibacterial property using agar well diffusion method at different concentration on standard human pathogenic bacterial strains. The zones of inhibitions for tested extracts were measured for each concentration on each bacterial strain tested in millimeter (mm) and showed zone of inhibitions were compared with the standard drug, ciprofloxacin. Results: The chloroform extract showed less activity compared to ethyl acetate and methanol extracts at low concentrations, but as the concentration increases the bactericidal activity was increased. The extracts showed more activity at 40mg/100μL. Among all extracts methanol extract showed more, but compared to ciprofloxacin the results on tested bacterial strains are not excellent. The extracts also showed more activity on gram negative bacterial strains. The extracts showed more activity on S. typhimurium and S. pneumoniae and lower activity on S. aureus and E. coli. Conclusion: The results of the present study provides the evidence on antibacterial property of selected medicinal plant if they use in higher concentrations and there is a scope to further studies on isolation of antimicrobial compounds from this species. Research Article Antibacterial Activity of Borassus Flabellifer G Veda Priya 1 *, T Mallikarjuna Rao 2 and B Ganga Rao 1 1 AU College of Pharmaceutical Science, Andhra University, Visakhapatnam, Andhra Pradesh, India 2 MICGENE lab, Visakhapatnam, Andhra Pradesh, India. Dates: Received: 05 December, 2016; Accepted: 15 December, 2016; Published: 16 December, 2016 *Corresponding author: Veda Priya, Gummadi, Research Scholar, A.U College of Pharmaceuti- cal Sciences, Andhra University, Visakhapatnam, AP, India-530 003, Tel: +91 8106572834; E-mail: Keywords: Borassus flabellifer; Roots and Antimicro- bial activity https://www.peertechz.com Introduction The microorganisms are becoming resistant to the present day using drugs due to different reasons [1]. This increase in resistance to the drugs automatically increases the use of antibiotics in adequate manner and leads to development of multi-drug resistant microorganisms including bacteria and also finally leads to increase the untreatable diseases [2]. So, there is a need to identify and develop the new antimicrobial agents with broad activity. Plants are the main sources to the humans since olden days for treating different diseases [3]. As the science and technology developing, isolation of pure molecules/compounds was increased from crude drugs of medicinal plants and have been using as antibiotics, but as above said present day drugs became less susceptible to microorganisms [4]. Now, there is an immediate action have to take in the isolation of new anti microbial compounds from unnoticed medicinal plants or known medicinal plants with use of technology. In this point of view, the present study was aimed to identify the antibacterial activity of Borassus flabellifer. B. flabellifer is commonly known as dumb plam native to Indian sub-subcontinent belongs to the family Arecaceae [5]. Different parts of this plants have been using since ancient times for different purposes including medicinally [6]. But, there very less scientific evidences present on their biological activities of different parts of this plant. So, we selected the roots part of the B. flabellifer for evaluation of antimicrobial activity on different human pathogenic bacterial strains. Materials and Methods Chemicals and drugs The chemicals used in the present study were analytical grade from Merk. The standard drug ciprofloxacin was purchased from Apollo pharmacy (Made Dr. Reddy’s). Collection of plant materials and preparation of ex- tracts The plant materials Borassus flabellifer was collected at near Bheemili region, Visakhapatnam, Andhra Pradesh and