System of Systems as a Solution to Mitigate the Spread of Covid-19 Hana Yousuf , Asma Y. Zainal , and Said A. Salloum Abstract System of systems is a compilation of systems that focus on a specic task or a system by combining multiple resources to create complicated task-oriented or dedicated systems that combine their resources and skills to develop a new, more complicated system with higher capability and performance than the individual systems. The paper will dene the System of Systems in terms of its architecture and the importance of having a System of System; then, it will dene Covid-19s spread and effect on economics. After that, it will describe System of Systems in the medical sector as a case study in terms of mitigating Covid-19 and the challenges. Finally, the solutions are provided, where different applications can be combined to operate in real-time and assist the government agencies and medical staff in operating effectively. Keywords System of systems Á Mitigation Á Solution Á Corona Á Covid-19 1 Introduction Around the turn of the new millennium, most of the world did not have any of cial policies with respect to best practices and recommendations for implementing, in case of a new pandemic or a new strain of a virus that could damage the economy of the entire world. There has been an instance of such deadly pandemics in the past, H. Yousuf Faculty of Engineering & IT, The British University in Dubai, Dubai, UAE A. Y. Zainal Faculty of Business Management, The British University in Dubai, Dubai, UAE S. A. Salloum (&) School of Science, Engineering, and Environment, University of Salford, Salford, UK e-mail: ssalloum@sharjah.ac.ae S. A. Salloum Machine Learning and NLP Research Group, Department of Computer Science, University of Sharjah, Sharjah, UAE © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022 A.-E. Hassanien et al. (eds.), Advances in Data Science and Intelligent Data Communication Technologies for COVID-19, Studies in Systems, Decision and Control 378, https://doi.org/10.1007/978-3-030-77302-1_5 77