Professional Med J 2017;24(9):1306-1309. www.theprofesional.com STROKE 1306 The Professional Medical Journal www.theprofesional.com STROKE; COMMON FACTORS LEADING IN YOUNG LOCAL POPULATION. Mehr Imran 1 , Muhammad Arslan 2 , Muhammad Umair Fiaz 3 , Ayesha Khalid 4 ORIGINAL PROF-3949 ABSTRACT… Objectives: To determine the frequency of common factors leading to stroke in young local population. Study Design: It is Descriptive Cross-Sectional study. Setting: Medical foor, DHQ, Hospital, Faisalabad. Period of Study: 6 Months, September, 2016 to February, 2017. Methodology: A total of 150 diagnosed cases of stoke between 18-40 years of age of either gender were enrolled in this trial. We excluded all those cases with recurrent history of cerebrovascular accidents, space occupying lesion, head injury, hypoglycemia, transient ischemic attack, CNS infection. We used CT brain showing either infarct or hemorrhage. After a detailed history from patient/relative including the common factors of stroke, all patients undergoing thorough physical examination, CT/MRI Scan brain, lipid profle and fasting blood glucose measurement to rule out the presence/absence of hypertension, smoking, Dyslipidemia and diabetes mellitus being the common risk factors. Results: Age distribution shows 38% (n=57) were between 18-30 years while 62% (n=93) between 31-40 years, mean+sd was calculated as 35.21+6.47 years. (Table-I) Gender distribution shows 64% (n=96) male and 36% (n=54) females. (Table-II). Frequency of common factors leading to stroke in young adults reveals hypertension in 60.67% (n=91), diabetes mellitus in 41.33% (n=62), smoking in 31.33% (n=47) and dyslipidemia in 23.33% (n=35). Conclusion: The results of the study conclude that among common factors hypertension, smoking, dyslipidemia and diabetes mellitus are the leading causes of stroke and these factors are modifable and by controlling on these factors, the frequency of stroke in young adults may be avoided. Key words: Stroke, Young adults, Causes, Hypertension, Smoking, Dyslipidemia and Diabetes Mellitus. 1. MBBS, FCPS (Med.) Senior Registrar, Medical Unit DHQ, Hospital, Faisalabad. 2. MBBS Medical Offcer, RHC, Faisalabad. 3. MBBS Casualty Medical Offcer, THQ, Hospital, Jaranwala 4. MBBS Correspondence Address: Dr. Muhammad Umair Fiaz, H# P-567, Rustam Chowk, Imran Road, Khayaban Colony#2, Madina Town, Faisalabad, Pakistan. Ihiii64@yahoo.com Article received on: 24/03/2017 Accepted for publication: 15/06/2017 Received after proof reading: 08/09/2017 Article Citation: Imran M, Arslan M, Fiaz MU, Khalid A. Stroke; common factors leading in young local population. Professional Med J 2017;24(9):1306-1309. DOI: 10.17957/TPMJ/17.3949 INTRODUCTION Stroke is defned as the acute loss of focal and at times global cerebral function; the symptoms lasting for more than 24 hours or leading to death and with no apparent cause other than vascular origin. 1 Transient ischemic attacks (TIA) and stroke are highly prevalent in our country. A recent community-based survey estimated 21.8% cases of stroke and/or TIA in Karachi City. 2 Stroke- specifc fatality is ranged between 7% to 20% in multiple local studies. Around 63% among all stroke sufferers may develop the complications while upto 89% of the cases are dependent for daily living activities. 3 Our data regarding risk factor for stroke is consistent with the Western world where most of the cases are found with smoking, diabetes mellitus, hypertension, dyslipidemia and cardiac disease. 3-4 Stroke is signifcantly higher in old age group but previous data reveals 18% of the cases are younger, which is a strong indicator for Pakistan with the fact that a large proportion of our population is young adults. 5-7 Previous data regarding the rate of risk factors of stroke reveals that the common risk factors in younger age group are dyslipidemia, diabetes mellitus, hypertension and smoking. 8-10 This study aimed to record the rate of risk factors of young stroke in our population so that this issue may be high lightened and to control these modifable risk factors thus preventing this morbidity in young age group. DOI: 10.17957/TPMJ/17.3949